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Decreased fragile histidine triad gene protein expression is associated with worse prognosis in oral squamous carcinoma
Journal article   Open access   Peer reviewed

Decreased fragile histidine triad gene protein expression is associated with worse prognosis in oral squamous carcinoma

Leana A Guerin, Henry T Hoffman, M Bridget Zimmerman and Robert A Robinson
Archives of pathology & laboratory medicine (1976), Vol.130(2), pp.158-164
02/2006
DOI: 10.5858/2006-130-158-DFHTGP
PMID: 16454554
url
https://doi.org/10.5858/2006-130-158-DFHTGPView
Published (Version of record) Open Access

Abstract

Fragile histidine triad (FHIT) gene is thought to be a tumor suppressor; abnormalities in expression have been reported in a variety of neoplasms.
Immunohistochemistry Carcinoma, Squamous Cell - genetics Carcinoma, Squamous Cell - metabolism Humans Middle Aged Acid Anhydride Hydrolases - metabolism Male Mouth Neoplasms - metabolism Loss of Heterozygosity Neoplasm Proteins - metabolism Carcinoma, Squamous Cell - diagnosis Disease-Free Survival Mouth Neoplasms - diagnosis Acid Anhydride Hydrolases - genetics Aged, 80 and over Biomarkers, Tumor - metabolism Adult Female Aged DNA, Neoplasm - analysis Neoplasm Proteins - genetics Neoplasm Staging Mouth Neoplasms - genetics Microsatellite Repeats

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