Journal article
Deep brain stimulation targeting the Globus pallidus internus for Parkinson's disease and Tourette syndrome
Clinical parkinsonism & related disorders, Vol.3, p.100077
2020
DOI: 10.1016/j.prdoa.2020.100077
PMCID: PMC8298847
PMID: 34316655
Abstract
We present a case with co-existing Parkinson's disease and Tourette syndrome. Patient takes aripiprazole for Tourette syndrome, which unfortunately worsens his parkinsonian symptoms. We placed deep brain stimulation targeting the Globus pallidus internus. Strikingly, his parkinsonian motor symptoms and his tics are both well controlled with deep brain stimulation.
•Patients with Tourette syndrome and Parkinson's disease may benefit from GPi DBS.•Higher frequency (130 Hz) GPi DBS may be helpful for tics.•Lower pulse width (60 μs) could be beneficial in Tourette syndrome.•Empirical combinations of pulse width and frequency should be liberally employed to maximize benefit.
Details
- Title: Subtitle
- Deep brain stimulation targeting the Globus pallidus internus for Parkinson's disease and Tourette syndrome
- Creators
- Qiang Zhang - University of IowaTeri R. Thomsen - University of Iowa Hospitals and Clinics
- Resource Type
- Journal article
- Publication Details
- Clinical parkinsonism & related disorders, Vol.3, p.100077
- DOI
- 10.1016/j.prdoa.2020.100077
- PMID
- 34316655
- PMCID
- PMC8298847
- NLM abbreviation
- Clin Park Relat Disord
- ISSN
- 2590-1125
- eISSN
- 2590-1125
- Publisher
- Elsevier Ltd
- Grant note
- DOI: 10.13039/100000065, name: NINDS; DOI: 10.13039/100000065, name: NINDS; DOI: 10.13039/100008893, name: University of Iowa
- Language
- English
- Date published
- 2020
- Academic Unit
- Neurology
- Record Identifier
- 9984302203102771
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