Defining Native Enhancer Function

Miles A Pufall

doi:10.1016/j.cels.2017.10.008

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Journal article

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Peer reviewed

Defining Native Enhancer Function

Miles A Pufall

Cell systems, Vol.5(4), pp.310-312

10/25/2017

DOI: 10.1016/j.cels.2017.10.008

PMID: 29073368

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Abstract

CRISPR inhibition is used to ablate the activity of regulatory elements alone and in combination, functionally linking regulatory elements to genes and revealing the logic of how these elements collaborate in their native genomic context.

Estrogen Receptor alpha

Enhancer Elements, Genetic

Genomics

Clustered Regularly Interspaced Short Palindromic Repeats

Gene Expression Regulation

Details

Title: Subtitle: Defining Native Enhancer Function
Creators: Miles A Pufall - Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA, USA. Electronic address: miles-pufall@uiowa.edu
Resource Type: Journal article
Publication Details: Cell systems, Vol.5(4), pp.310-312
Publisher: United States
DOI: 10.1016/j.cels.2017.10.008
PMID: 29073368
ISSN: 2405-4712
eISSN: 2405-4720
Grant note: P30 CA086862 / NCI NIH HHS
Language: English
Date published: 10/25/2017
Academic Unit: Biochemistry and Molecular Biology
Record Identifier: 9984025270502771

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