Journal article
Defining anxious depression: a review of the literature
CNS spectrums, Vol.18(5), pp.252-260
10/2013
DOI: 10.1017/S1092852913000114
PMCID: PMC3773528
PMID: 23507190
Abstract
The diagnosis of anxious depression is presently inconsistent. The many different definitions of anxious depression have complicated its diagnosis, leading to clinical confusion and inconsistencies in the literature. This article reviewed the extant literature in order to identify the varying definitions of anxious depression, which were then compared using Feighner's diagnostic criteria. Notably, these suggest a different clinical picture of patients with anxious depression. For instance, relying on The International Classification of Diseases (ICD) or Diagnostic and Statistical Manual of Mental Disorders (DSM) diagnoses yields a clinical picture of a comparatively mild or transient disorder; in contrast, using dimensional criteria such as DSM criteria combined with additional rating scales—most commonly the anxiety somatization factor score from the Hamilton Depression Rating Scale (HAM-D)—yields a more serious clinical picture. The evidence reviewed here suggests that defining anxious depression in a dimensional manner may be the most useful and clinically relevant way of differentiating it from other types of mood and anxiety disorders, and of highlighting the most clinically significant differences between patients with anxious depression versus depression or anxiety alone.
Details
- Title: Subtitle
- Defining anxious depression: a review of the literature
- Creators
- Dawn F Ionescu - Experimental Therapeutics & Pathophysiology Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USAMark J Niciu - Experimental Therapeutics & Pathophysiology Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USAIoline D Henter - Experimental Therapeutics & Pathophysiology Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USACarlos A Zarate - Experimental Therapeutics & Pathophysiology Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA
- Resource Type
- Journal article
- Publication Details
- CNS spectrums, Vol.18(5), pp.252-260
- DOI
- 10.1017/S1092852913000114
- PMID
- 23507190
- PMCID
- PMC3773528
- NLM abbreviation
- CNS Spectr
- ISSN
- 1092-8529
- eISSN
- 2165-6509
- Publisher
- Cambridge University Press (CUP); New York, USA
- Number of pages
- 9
- Language
- English
- Date published
- 10/2013
- Academic Unit
- Psychiatry; Iowa Neuroscience Institute
- Record Identifier
- 9984003488102771
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