Journal article
Delay in desmopressin therapy: Disaster in waiting
Journal of clinical pharmacy and therapeutics, Vol.47(12), pp.2376-2378
2022
DOI: 10.1111/jcpt.13807
PMCID: PMC10100437
PMID: 36376238
Appears in UI Libraries Support Open Access
Abstract
What Is Known and Objective Central diabetes insipidus (DI) is a complex disease that requires firm adherence to desmopressin therapy. There is little information on the onset of hypernatremia after withdrawal of desmopressin. Case Summary We present a case of an elderly woman with central DI whose serum sodium jumped from 141 to 171 mEq/L after 48-72 h of holding oral desmopressin. Her DI crisis resolved with intravenous desmopressin and free water administration. What Is New and Conclusion Based on this precipitous onset of DI crisis, we recommend not withholding desmopressin for more than 24 h.
Details
- Title: Subtitle
- Delay in desmopressin therapy: Disaster in waiting
- Creators
- Christian Kroll - University of Iowa Hospitals and ClinicsArya Zandvakili - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Journal of clinical pharmacy and therapeutics, Vol.47(12), pp.2376-2378
- DOI
- 10.1111/jcpt.13807
- PMID
- 36376238
- PMCID
- PMC10100437
- NLM abbreviation
- J Clin Pharm Ther
- ISSN
- 0269-4727
- eISSN
- 1365-2710
- Publisher
- Wiley
- Number of pages
- 3
- Language
- English
- Electronic publication date
- 11/14/2022
- Date published
- 2022
- Academic Unit
- Internal Medicine
- Record Identifier
- 9984322346002771
Metrics
21 Record Views