Journal article
Delirium prevention and treatment in the emergency department (ED): a systematic review protocol
BMJ open, Vol.10(10), pp.e037915-e037915
10/06/2020
DOI: 10.1136/bmjopen-2020-037915
PMID: 33028553
Abstract
IntroductionDelirium is a dangerous syndrome of acute brain dysfunction that is common in the emergency department (ED), especially among the geriatric population. Most systematic reviews of interventions for delirium prevention and treatment have focused on inpatient settings. Best practices of effective delirium care in ED settings have not been established. The primary objective of this study is to identify pharmacologic and non-pharmacologic interventions as applied by physicians, nursing staff, pharmacists and other ED personnel to prevent incident delirium and to shorten the severity and duration of prevalent delirium in a geriatric population within the ED.Methods and analysisSearches using subject headings and keywords will be conducted from database inception through June 2020 in MEDLINE, EMBASE, Web of Science, PsychINFO, CINAHL, ProQuest Dissertations and Theses Global and Cochrane CENTRAL as well as grey literature. Database searches will not be limited by date or language. Two reviewers will identify studies describing any interventions for delirium prevention and/or treatment in the ED. Disagreements will be settled by a third reviewer. Pooled data analysis will be performed where possible using Review Manager. Risk ratios and weighted difference of means will be used for incidence of delirium and other binary outcomes related to delirium, delirium severity or duration of symptoms, along with 95% CIs. Heterogeneity will be measured by calculating I2, and a forest plot will be created. If significant heterogeneity is identified, metaregression is planned using OpenMeta to identify possible sources of heterogeneity.Ethics and disseminationThis is a systematic review of previously conducted research; accordingly, it does not constitute human subjects research needing ethics review. This review will be prepared as a manuscript and submitted for publication to a peer-reviewed journal, and the results will be presented at conferences.PROSPERO trial registration numberCRD42020169654.
Details
- Title: Subtitle
- Delirium prevention and treatment in the emergency department (ED): a systematic review protocol
- Creators
- Elijah Blue Dahlstrom - Department of Emergency Medicine, University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa City, Iowa, USAJin Ho Han - Department of Emergency Medicine, Vanderbilt University, Nashville, Tennessee, USAHeather Healy - University of Iowa Libraries, University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa City, Iowa, USAMaura Kennedy - Department of Emergency Medicine, Massachusetts General Hospital, Boston, Massachusetts, USAGlenn Arendts - The University of Western Australia, Perth, Western Australia, AustraliaJacques Lee - University of Toronto, Toronto, Ontario, CanadaChris Carpenter - Department of Emergency Medicine, Washington University in Saint Louis, Saint Louis, Missouri, USASangil Lee - Department of Emergency Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA
- Resource Type
- Journal article
- Publication Details
- BMJ open, Vol.10(10), pp.e037915-e037915
- DOI
- 10.1136/bmjopen-2020-037915
- PMID
- 33028553
- NLM abbreviation
- BMJ Open
- ISSN
- 2044-6055
- eISSN
- 2044-6055
- Grant note
- name: University of Iowa Hospitals and Clinics Department of Emergency Medicine
- Language
- English
- Date published
- 10/06/2020
- Academic Unit
- Emergency Medicine; Injury Prevention Research Center; Hardin Library
- Record Identifier
- 9984077781202771
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