Journal article
Delivery Room Resuscitation and Short-Term Outcomes in Moderately Preterm Infants
The Journal of pediatrics, Vol.195, pp.33-38.e2
04/2018
DOI: 10.1016/j.jpeds.2017.11.039
PMCID: PMC5869086
PMID: 29306493
Abstract
To describe the frequency and extent of delivery room resuscitation and evaluate the association of delivery room resuscitation with neonatal outcomes in moderately preterm (MPT) infants.
This was an observational cohort study of MPT infants delivered at 290/7 to 336/7 weeks' gestational age (GA) enrolled in the Neonatal Research Network MPT registry. Infants were categorized into 5 groups based on the highest level of delivery room intervention: routine care, oxygen and/or continuous positive airway pressure, bag and mask ventilation, endotracheal intubation, and cardiopulmonary resuscitation including chest compressions and/or epinephrine use. The association of antepartum and intrapartum risk factors and discharge outcomes with the intensity of resuscitation was evaluated.
Of 7014 included infants, 1684 (24.0%) received routine care and no additional resuscitation, 2279 (32.5%) received oxygen or continuous positive airway pressure, 1831 (26.1%) received bag and mask ventilation, 1034 (14.7%) underwent endotracheal intubation, and 186 (2.7%) received cardiopulmonary resuscitation. Among the antepartum and intrapartum factors, increasing GA, any exposure to antenatal steroids and prolonged rupture of membranes decreased the likelihood of receipt of all levels of resuscitation. Infants who were small for GA (SGA) had increased risk of delivery room resuscitation. Among the neonatal outcomes, respiratory support at 28 days, days to full oral feeds and length of stay were significantly associated with the intensity of delivery room resuscitation. Higher intensity of resuscitation was associated with increased risk of mortality.
The majority of MPT infants receive some level of delivery room resuscitation. Increased intensity of delivery room interventions was associated with prolonged respiratory and nutritional support, increased mortality, and a longer length of stay.
Details
- Title: Subtitle
- Delivery Room Resuscitation and Short-Term Outcomes in Moderately Preterm Infants
- Creators
- Monika Bajaj - Wayne State UniversityGirija Natarajan - Wayne State UniversitySeetha Shankaran - Wayne State UniversityMyra Wyckoff - The University of Texas Southwestern Medical CenterAbbot R. Laptook - Brown UniversityEdward F. Bell - University of IowaBarbara J. Stoll - The University of Texas Health Science Center at HoustonWaldemar A. Carlo - University of Alabama at BirminghamBetty R. Vohr - Brown UniversityShampa Saha - RTI InternationalKrisa P. Van Meurs - Stanford UniversityPablo J. Sanchez - Nationwide Children's HospitalCarl T. D'Angio - University of RochesterRosemary D. Higgins - National Institutes of HealthAbhik Das - RTI InternationalNancy Newman - Case Western Reserve UniversityMichele C. Walsh - Case Western Reserve UniversityRichard A. Polin - Columbia UniversityMartin Keszler - Brown UniversityAngelita M. Hensman - Brown UniversityElisa Vieira - Brown UniversityAnna Marie Hibbs - Case Western Reserve UniversityBonnie S. Siner - Case Western Reserve UniversityWilliam E. Truog - Children's Mercy HospitalEugenia K. Pallotto - Children's Mercy HospitalHoward W. Kilbride - Children's Mercy HospitalCheri Gauldin - Children's Mercy HospitalAnne Holmes - Children's Mercy HospitalKathy Johnson - Children's Mercy HospitalBrenda B. Poindexter - Cincinnati Children's Hospital Medical CenterKurt Schibler - Cincinnati Children's Hospital Medical CenterSuhas G. Kallapur - Cincinnati Children's Hospital Medical CenterCathy Grisby - Cincinnati Children's Hospital Medical CenterBarbara Alexander - Cincinnati Children's Hospital Medical CenterEstelle E. Fischer - Cincinnati Children's Hospital Medical CenterLenora Jackson - Cincinnati Children's Hospital Medical CenterKristin Kirker - Cincinnati Children's Hospital Medical CenterJennifer Jennings - Cincinnati Children's Hospital Medical CenterSandra Wuertz - Cincinnati Children's Hospital Medical CenterGreg Muthig - Cincinnati Children's Hospital Medical CenterC. Michael Cotten - Duke UniversityRonald N. Goldberg - Duke UniversityJoanne Finkle - Duke UniversityKimberley A. Fisher - Duke UniversityMatthew M. Laughon - Duke UniversityCarl L. Bose - Duke UniversityJanice Bernhardt - Duke UniversityCindy Clark - Duke UniversityDavid P. Carlton - Emory University Hospital MidtownEllen C. Hale - Emory University Hospital MidtownYvonne Loggins - Emory University Hospital MidtownDiane I. Bottcher - Emory University Hospital MidtownStephanie Wilson Archer - National Institutes of HealthGreg Sokol - Riley Hospital for ChildrenDianne E. Herron - Riley Hospital for ChildrenLeif D. Nelin - Nationwide Children's HospitalSudarshan R. Jadcherla - Nationwide Children's HospitalPatricia Luzader - Nationwide Children's HospitalNehal A. Parikh - Nationwide Children's HospitalMarliese Dion Nist - Nationwide Children's HospitalJennifer Fuller - Nationwide Children's HospitalJulie Gutentag - Nationwide Children's HospitalMarissa E. Jones - Nationwide Children's HospitalSarah McGregor - Nationwide Children's HospitalElizabeth Rodgers - Nationwide Children's HospitalJodi A. Ulloa - Nationwide Children's HospitalTara Wolfe - Nationwide Children's HospitalDennis Wallace - RTI InternationalKristin M. Zaterka-Baxter - RTI InternationalMargaret Crawford - RTI InternationalJenna Gabrio - RTI InternationalSarah Kandefer - RTI InternationalJeanette O'Donnell Auman - RTI InternationalDavid K. Stevenson - Lucile Packard Children's HospitalM. Bethany Ball - Lucile Packard Children's HospitalMelinda S. Proud - Lucile Packard Children's HospitalNamasivayam Ambalavanan - University of Alabama at BirminghamMonica V. Collins - University of Alabama at BirminghamShirley S. Cosby - University of Alabama at BirminghamUday Devaskar - University of California, Los AngelesMeena Garg - University of California, Los AngelesTeresa Chanlaw - University of California, Los AngelesRachel Geller - University of California, Los AngelesTarah T. Colaizy - University of IowaDan L. Ellsbury - University of IowaJane E. Brumbaugh - University of IowaKaren J. Johnson - University of IowaDonia B. Campbell - University of IowaJacky R. Walker - University of IowaKristi L. Watterberg - University of New MexicoRobin K. Ohls - University of New MexicoConra Backstrom Lacy - University of New MexicoSandy Sundquist Beauman - University of New MexicoCarol Hartenberger - University of New MexicoBarbara Schmidt - Hospital of the University of PennsylvaniaHaresh Kirpalani - Hospital of the University of PennsylvaniaSara B. DeMauro - Hospital of the University of PennsylvaniaNoah Cook - Hospital of the University of PennsylvaniaAasma S. Chaudhary - Hospital of the University of PennsylvaniaSoraya Abbasi - Hospital of the University of PennsylvaniaToni Mancini - Hospital of the University of PennsylvaniaDara Cucinotta - Hospital of the University of PennsylvaniaSatyan Lakshminrusimha - University of Rochester Medical CenterRonnie Guillet - University of Rochester Medical CenterAnn Marie Scorsone - University of Rochester Medical CenterJulianne Hunn - University of Rochester Medical CenterRosemary Jensen - University of Rochester Medical CenterHolly I.M. Wadkins - University of Rochester Medical CenterStephanie Guilford - University of Rochester Medical CenterAshley Williams - University of Rochester Medical CenterLuc P. Brion - The University of Texas Southwestern Medical CenterDiana M. Vasil - The University of Texas Southwestern Medical CenterLijun Chen - The University of Texas Southwestern Medical CenterLizette E. Torres - The University of Texas Southwestern Medical CenterKathleen A. Kennedy - The University of Texas Health Science Center at HoustonJon E. Tyson - The University of Texas Health Science Center at HoustonJulie Arldt-McAlister - The University of Texas Health Science Center at HoustonCarmen Garcia - The University of Texas Health Science Center at HoustonKaren Martin - The University of Texas Health Science Center at HoustonGeorgia E. McDavid - The University of Texas Health Science Center at HoustonSharon L. Wright - The University of Texas Health Science Center at HoustonAthina Pappas - University of Michigan–Ann ArborJohn Barks - Wayne State UniversityRebecca Bara - University of Michigan–Ann ArborShelley Handel - University of Michigan–Ann ArborDiane F. White - University of Michigan–Ann ArborMary Christensen - University of Michigan–Ann ArborStephanie A. Wiggins - University of Michigan–Ann ArborNational Institute of Child Health and Human Development Neonatal Research Network
- Resource Type
- Journal article
- Publication Details
- The Journal of pediatrics, Vol.195, pp.33-38.e2
- Publisher
- Elsevier Inc
- DOI
- 10.1016/j.jpeds.2017.11.039
- PMID
- 29306493
- PMCID
- PMC5869086
- ISSN
- 0022-3476
- eISSN
- 1097-6833
- Grant note
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (https://doi.org/10.13039/100009633) U10HD27904; U10HD21364; U10 HD68284; U10 HD27853; U10 HD40492; U10 HD27851; U10 HD27856; U10 HD68278; U10 HD36790; U10 HD27880; U10 HD34216; U10 HD68270; U10 HD53109; U10 HD53089; U10 HD68244; U10 HD68263; U10 HD40689; U10 HD21373; U10 HD21385 / National Center for Advancing Translational Sciences (https://doi.org/10.13039/100006108)
- Language
- English
- Date published
- 04/2018
- Academic Unit
- Stead Family Department of Pediatrics; Neonatology
- Record Identifier
- 9984353947402771
Metrics
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