Demographic differences in incidence for pituitary adenoma

Bradley D McDowell; Robert B Wallace; Ryan M Carnahan; Elizabeth A Chrischilles; Charles F Lynch; Janet A Schlechte

doi:10.1007/s11102-010-0253-4

Back

Demographic differences in incidence for pituitary adenoma

Journal article

Peer reviewed

Demographic differences in incidence for pituitary adenoma

Bradley D McDowell, Robert B Wallace, Ryan M Carnahan, Elizabeth A Chrischilles, Charles F Lynch and Janet A Schlechte

Pituitary, Vol.14(1), pp.23-30

03/2011

DOI: 10.1007/s11102-010-0253-4

PMCID: PMC3652258

PMID: 20809113

Files and links (1)

url

https://www.ncbi.nlm.nih.gov/pmc/articles/3652258View

Open Access

Abstract

Incidence estimates for pituitary adenomas vary widely, suggesting the effects of numerous risk factors or varying levels of tumor surveillance. We studied the epidemiology of pituitary adenomas using 2004-2007 data collected by 17 Surveillance, Epidemiology, and End Results Programs in the United States (N = 8,276). We observed that incidence rates generally increased with age and were higher in females in early life and higher in males in later life. Males are diagnosed with larger tumors on average than females. Diagnosis may be delayed for males, giving tumors a chance to grow larger before clinical detection. We also observed that American Blacks have higher incidence rates for pituitary adenomas compared with other ethnic groups. There are several potential explanations for this finding with some evidence that at least part of the effect may be due to differential diagnosis between races.

Pituitary Neoplasms - epidemiology

Pituitary Neoplasms - ethnology

Age Factors

Humans

Sex Factors

Female

Male

Details

Title: Subtitle: Demographic differences in incidence for pituitary adenoma
Creators: Bradley D McDowell - Holden Comprehensive Cancer Center, The University of Iowa, Iowa City, IA, 52242, USA. bradley-mcdowell@uiowa.edu
Robert B Wallace
Ryan M Carnahan
Elizabeth A Chrischilles
Charles F Lynch
Janet A Schlechte
Resource Type: Journal article
Publication Details: Pituitary, Vol.14(1), pp.23-30
DOI: 10.1007/s11102-010-0253-4
PMID: 20809113
PMCID: PMC3652258
NLM abbreviation: Pituitary
ISSN: 1386-341X
eISSN: 1573-7403
Publisher: United States
Grant note: 5 P30 CA086862-10 / NCI NIH HHS P20 CA103672 / NCI NIH HHS 5 P20 CA103672-05 / NCI NIH HHS 5 U18 HS016094 / AHRQ HHS U18 HS016094 / AHRQ HHS P30 CA086862 / NCI NIH HHS
Language: English
Date published: 03/2011
Academic Unit: Pharmacy; Epidemiology; Injury Prevention Research Center; Endocrinology and Metabolism; Holden Comprehensive Cancer Center; Internal Medicine
Record Identifier: 9983995028702771

Metrics

39 Record Views

89 Times Cited - Web of Science