Journal article
Demonstration of Multi- and Single-Reader Sample Size Program for Diagnostic Studies software
Proceedings of SPIE, the international society for optical engineering, Vol.9416, pp.94160E-94160E-11
02/2015
DOI: 10.1117/12.2083150
PMCID: PMC5589343
PMID: 28890592
Abstract
The recently released software
, written by Kevin Schartz and Stephen Hillis, performs sample size computations for diagnostic reader-performance studies. The program computes the sample size needed to detect a specified difference in a reader performance measure between two modalities, when using the analysis methods initially proposed by Dorfman, Berbaum, and Metz (DBM) and Obuchowski and Rockette (OR), and later unified and improved by Hillis and colleagues. A commonly used reader performance measure is the area under the receiver-operating-characteristic curve. The program can be used with typical common reader-performance measures which can be estimated parametrically or nonparametrically. The program has an easy-to-use step-by-step intuitive interface that walks the user through the entry of the needed information. Features of the software include the following: (1) choice of several study designs; (2) choice of inputs obtained from either OR or DBM analyses; (3) choice of three different inference situations: both readers and cases random, readers fixed and cases random, and readers random and cases fixed; (4) choice of two types of hypotheses: equivalence or noninferiority; (6) choice of two output formats: power for specified case and reader sample sizes, or a listing of case-reader combinations that provide a specified power; (7) choice of single or multi-reader analyses; and (8) functionality in Windows, Mac OS, and Linux.
Details
- Title: Subtitle
- Demonstration of Multi- and Single-Reader Sample Size Program for Diagnostic Studies software
- Creators
- Stephen L Hillis - Department of Radiology, University of Iowa, 3170 ML, 200 Hawkins Drive, Iowa City, IA USA 52242-1077Kevin M Schartz - Department of Radiology, University of Iowa, 3170 ML, 200 Hawkins Drive, Iowa City, IA USA 52242-1077
- Resource Type
- Journal article
- Publication Details
- Proceedings of SPIE, the international society for optical engineering, Vol.9416, pp.94160E-94160E-11
- DOI
- 10.1117/12.2083150
- PMID
- 28890592
- PMCID
- PMC5589343
- NLM abbreviation
- Proc SPIE Int Soc Opt Eng
- ISSN
- 0277-786X
- eISSN
- 1996-756X
- Publisher
- United States
- Grant note
- R01 EB013667 / NIBIB NIH HHS
- Language
- English
- Date published
- 02/2015
- Academic Unit
- Radiology; Biostatistics
- Record Identifier
- 9984051543602771
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