Journal article
Densitometric analysis of eccentric vascular stenoses: Comparison of CO 2 and iodinated contrast media
Academic radiology, Vol.3(12), pp.985-993
1996
DOI: 10.1016/S1076-6332(96)80029-8
Abstract
The authors compared the accuracies of CO
2 and iodinated contrast material in the densitometric quantification of eccentric vascular stenoses.
Five precision-machined eccentric phantom stenoses of 50%, 60%, 70%, 80%, and 90% cross-sectional area narrowing were integrated into a pulsatile ex vivo flow model, imaged with digital subtraction angiography (DSA), and analyzed with densitometry. Relationships between the actual and measured (densitometric) degree of cross-sectional area narrowing were evaluated by using linear regression analysis and paired Student
t tests. Comparison measurements were obtained in en face and profile projections. In addition, the effect of iodinated contrast material concentration was evaluated over a range of dilutions (47–282 mg iodine per milliliter).
CO
2 yielded significantly more accurate results than did iodinated contrast material (282 mg iodine per milliliter) in the 50%, 60%, and 70% stenosis models when imaging was performed en face (
P < .005). The best overall correlation was observed with CO
2 DSA when imaging in profile (slope = 0.91, intercept = 2.42% actual stenosis,
r = .99). The accuracy of densitometric stenosis estimation was inversely related to the concentration of iodinated contrast material.
CO
2 DSA densitometry, under the conditions of these experiments, yields quantitative measures of relative cross-sectional area narrowing that are comparable with, and under some circumstances surpass, those obtained with iodinated contrast material-based DSA. In this model, CO
2 was more useful than iodinated contrast material in 50%–70% stenosis when imaging in the least-optimal plane of stenosis quantification, the en face projection.
Details
- Title: Subtitle
- Densitometric analysis of eccentric vascular stenoses: Comparison of CO 2 and iodinated contrast media
- Creators
- Carl M. Black - University of Iowa Hospitals and ClinicsElvira V. Lang - University of Iowa Hospitals and ClinicsCatherine A. Kusnick - University of Iowa Hospitals and ClinicsMaria Siebes - University of Iowa Hospitals and ClinicsWilliam Barnhart - University of IowaKevin S. Berbaum - University of IowaEric A. Hoffman - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Academic radiology, Vol.3(12), pp.985-993
- Publisher
- Elsevier Inc
- DOI
- 10.1016/S1076-6332(96)80029-8
- ISSN
- 1076-6332
- eISSN
- 1878-4046
- Language
- English
- Date published
- 1996
- Academic Unit
- Radiology; Roy J. Carver Department of Biomedical Engineering; Internal Medicine
- Record Identifier
- 9984318789802771
Metrics
3 Record Views