Journal article
Depression and stages of Huntington's disease
The journal of neuropsychiatry and clinical neurosciences, Vol.17(4), pp.496-502
2005
DOI: 10.1176/jnp.17.4.496
PMID: 16387989
Abstract
Individuals with manifest Huntington's disease (HD) were interviewed with regard to the presence, frequency, and severity of depression symptoms to better characterize depressed mood across the disease course in HD. Rates of depression were more than twice that found in the general population. One-half reported that they had sought treatment for depression, and more than 10% reported having at least one suicide attempt. The proportion of HD patients endorsing significant depression diminished with disease progression. Despite the public health impact of depression, available treatments are underutilized in HD, and research is needed to document the efficacy and effectiveness of standard depression treatments in this population.
Details
- Title: Subtitle
- Depression and stages of Huntington's disease
- Creators
- Jane S Paulsen - University of Iowa, 1-305 Medical Education Building, Iowa City, IA 52242, USA. jane-paulsen@uiowa.eduCarissa NehlKarin Ferneyhough HothJason E KanzMichelle BenjaminRachel ConybeareBradley McDowellBeth Turner
- Resource Type
- Journal article
- Publication Details
- The journal of neuropsychiatry and clinical neurosciences, Vol.17(4), pp.496-502
- Publisher
- United States
- DOI
- 10.1176/jnp.17.4.496
- PMID
- 16387989
- ISSN
- 0895-0172
- eISSN
- 1545-7222
- Grant note
- T32 AG000214 / NIA NIH HHS NS 40068 / NINDS NIH HHS MH 65830 / NIMH NIH HHS MH 01579 / NIMH NIH HHS
- Language
- English
- Date published
- 2005
- Academic Unit
- Psychiatry; Psychological and Brain Sciences; Iowa Neuroscience Institute; Holden Comprehensive Cancer Center
- Record Identifier
- 9984066384302771
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