Depression following traumatic brain injury: a 1 year longitudinal study

Ricardo E. Jorge; Robert G. Robinson; Stephan V. Arndt; Sergio E. Starkstein; Alfred W. Forrester; Fred Geisler

doi:10.1016/0165-0327(93)90047-N

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Depression following traumatic brain injury: a 1 year longitudinal study

Journal article

Peer reviewed

Depression following traumatic brain injury: a 1 year longitudinal study

Ricardo E. Jorge, Robert G. Robinson, Stephan V. Arndt, Sergio E. Starkstein, Alfred W. Forrester and Fred Geisler

Journal of affective disorders, Vol.27(4), pp.233-243

04/01/1993

DOI: 10.1016/0165-0327(93)90047-N

PMID: 8509524

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Abstract

A group of 66 patients hospitalized for the treatment of closed head injury, were assessed for the presence of mood disorders during their hospital admission and at 3, 6 and 12 months follow-up. A total 28 patients met DSM-III-R diagnostic criteria for major depression at some time during the study (17 in the acute stage, 11 during follow-up). The mean duration of major depression was 4.7 months. However, there appeared to be a group of transiently depressed patients (41%) who where depressed inhospital but were no longer depressed at 3 months follow-up. Throughout the follow-up period, major depression showed a strong relationship with poor social functioning. There was not, however, a consistent relationship between depression and quantitative measures of either physical or cognitive impairment. Location of the brain lesion was associated with the development of major depression only in the acute stage. Transient depressive syndromes were associated with left dorsolateral frontal and/or left basal ganglia lesions.

major depression

traumatic brain injury

Details

Title: Subtitle: Depression following traumatic brain injury: a 1 year longitudinal study
Creators: Ricardo E. Jorge - University of Iowa
Robert G. Robinson - University of Iowa
Stephan V. Arndt - University of Iowa
Sergio E. Starkstein - Instituto de Neurología Cognitiva
Alfred W. Forrester - Johns Hopkins Medicine
Fred Geisler - University of Maryland Medical System
Resource Type: Journal article
Publication Details: Journal of affective disorders, Vol.27(4), pp.233-243
DOI: 10.1016/0165-0327(93)90047-N
PMID: 8509524
ISSN: 0165-0327
eISSN: 1573-2517
Publisher: Elsevier B.V
Number of pages: 11
Language: English
Date published: 04/01/1993
Academic Unit: Psychiatry; Biostatistics; Nursing; Injury Prevention Research Center
Record Identifier: 9985132072402771

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