Journal article
Depression in the early stages of Huntington disease
Neurodegenerative disease management, Vol.1(5), pp.407-414
10/01/2011
DOI: 10.2217/NMT.11.45
PMCID: PMC3430381
PMID: 22942903
Abstract
Huntington disease (HD) has traditionally been considered a movement disorder, but cognitive and psychiatric symptoms also prominently factor into its clinical presentation. Depression is one of the most common psychiatric disturbances in HD, with its prevalence highest in manifest disease during stage 2, but it is also present during the illness prodrome (the period before manifestation of motor symptoms). Identification and treatment of depression in individuals with the HD mutation is an essential part of clinical management in this population, especially owing to the high risk of suicide. This article summarizes what is currently known about the presentation and treatment of depression in the early stages of HD and provides advice to clinicians treating this population.
Details
- Title: Subtitle
- Depression in the early stages of Huntington disease
- Creators
- Eric A. Epping - Roy J. and Lucille A. Carver College of MedicineJane S. Paulsen - Roy J. and Lucille A. Carver College of Medicine
- Resource Type
- Journal article
- Publication Details
- Neurodegenerative disease management, Vol.1(5), pp.407-414
- Publisher
- Future Medicine Ltd
- DOI
- 10.2217/NMT.11.45
- PMID
- 22942903
- PMCID
- PMC3430381
- ISSN
- 1758-2024
- eISSN
- 1758-2032
- Number of pages
- 8
- Grant note
- NS40068 / National Institute of Neurological Disorders and Stroke; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Neurological Disorders & Stroke (NINDS) CHDI Foundation, Inc R01NS040068 / NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Neurological Disorders & Stroke (NINDS) National Institutes for Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA
- Language
- English
- Date published
- 10/01/2011
- Academic Unit
- Psychiatry; Psychological and Brain Sciences
- Record Identifier
- 9984288735102771
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