Journal article
Depressive symptoms in the elderly: Association with total white blood cell count
Progress in neuro-psychopharmacology & biological psychiatry, Vol.19(5), pp.849-860
09/1995
DOI: 10.1016/0278-5846(95)00115-C
PMID: 8539423
Abstract
1. 1. The white blood cell (WBC) count in those with high depressive symptoms and non-depressed participants in the Established Populations for Epidemiologic Studies of the Elderly (EPESE) were compared. 2. 2. Of 3769 participants 10.8% had high depressive symptoms as assessed by the Centers for Epidemiologic Studies Depression (CES-D) Scale. The mean white blood cell count was higher in the high depressive symptoms group compared to the non-depressed group (6.8 ± 0.12 × 109 WBC /1 and 6.5 ± 0.03 × 109 WBC/1, respectively, p < 0.01). 3. 3. Because older adults frequently have disabling chronic conditions which could both influence their leukocyte count and cause depressive symptoms, models were developed which controlled for the potential confounding. Even after adjusting for potential confounders, high depressive symptoms were still associated with higher white blood cell counts. © 1995.
Details
- Title: Subtitle
- Depressive symptoms in the elderly: Association with total white blood cell count
- Creators
- S.Lori Brown - National Institute on AgingMarcel E. Salive - National Institute on AgingJack M. Guralnik - National Institute on AgingRobert B. Wallace - University of IowaAdrian M. Ostfeld - Yale UniversityDan Blazer - Duke University
- Resource Type
- Journal article
- Publication Details
- Progress in neuro-psychopharmacology & biological psychiatry, Vol.19(5), pp.849-860
- DOI
- 10.1016/0278-5846(95)00115-C
- PMID
- 8539423
- NLM abbreviation
- Prog Neuropsychopharmacol Biol Psychiatry
- ISSN
- 0278-5846
- eISSN
- 1878-4216
- Language
- English
- Date published
- 09/1995
- Academic Unit
- Epidemiology; Injury Prevention Research Center; Internal Medicine
- Record Identifier
- 9984364421402771
Metrics
9 Record Views