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Dermatomyositis Associated with Myelofibrosis following Polycythemia Vera
Journal article   Open access   Peer reviewed

Dermatomyositis Associated with Myelofibrosis following Polycythemia Vera

Naomi Fei and Sarah Sofka
Case reports in hematology, Vol.2017(2017), pp.1-4
01/01/2017
DOI: 10.1155/2017/9091612
PMCID: PMC5474248
PMID: 28660085
url
https://doi.org/10.1155/2017/9091612View
Published (Version of record) Open Access

Abstract

Dermatomyositis (DM) is a unique inflammatory myopathy with clinical findings of proximal muscle weakness, characteristic rash, and elevated muscle enzymes. The association of DM and malignancy, most commonly adenocarcinoma, is well known. There have been few case reports of primary myelofibrosis associated with DM. We present the case of a 69-year-old male with a history of polycythemia vera (PV) who developed proximal muscle weakness, dysphagia, and rash. He was found to have elevated creatinine kinase and skin biopsy was consistent with DM. Due to persistent pancytopenia a bone marrow biopsy was performed and showed postpolycythemic myelofibrosis. To our knowledge, this is the first case reported of this unique association.
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