Descriptive Epidemiology of Central Line-Associated Bloodstream Infections at an Academic Medical Center in Iowa, 2019–2022

Elaine M. Harrington; Kathryn Trautman; Mary Beth Davis; Kristin Varzavand; Holly Meacham; Angelique Dains; Alexandre R. Marra; Jennifer McDanel; Lynnette Kenne; Beth Hanna; James P. Murphy; Daniel J. Diekema; Melanie Wellington; Karen B. Brust; Takaaki Kobayashi; Oluchi J. Abosi

doi:10.1016/j.ajic.2023.09.021

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Descriptive Epidemiology of Central Line-Associated Bloodstream Infections at an Academic Medical Center in Iowa, 2019–2022

Journal article

Peer reviewed

Descriptive Epidemiology of Central Line-Associated Bloodstream Infections at an Academic Medical Center in Iowa, 2019–2022

Elaine M. Harrington, Kathryn Trautman, Mary Beth Davis, Kristin Varzavand, Holly Meacham, Angelique Dains, Alexandre R. Marra, Jennifer McDanel, Lynnette Kenne, Beth Hanna, …

American journal of infection control, Vol.52(4), pp.436-442

04/2024

DOI: 10.1016/j.ajic.2023.09.021

PMID: 37827243

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Abstract

Background Central line-associated bloodstream infections (CLABSIs) increased nationally during the COVID-19 pandemic. We described CLABSIs at our institution during 2019–2022. Methods This retrospective observational study examined CLABSIs among adult inpatients at an 866-bed teaching hospital in the Midwest. CLABSI incidence was trended over time and compared to monthly COVID-19 admissions. Manual chart review was performed to obtain patient demographics, catheter-associated variables, pathogens, and clinical outcomes. Results We identified 178 CLABSIs. The CLABSI incidence (cases per 1000 line-days) tripled in October 2020 as COVID-19 admissions increased. CLABSIs in 2020 were more frequently due to coagulase-negative staphylococci and occurred in the intensive care units 7+ days after central line insertion. The CLABSI incidence normalized in early 2021 and did not increase during subsequent COVID-19 surges. Throughout 2019–2022, about half of non-tunneled central venous catheters involved in CLABSI were placed emergently. One-quarter of CLABSIs involved multiple central lines. Chlorhexidine skin treatment adherence was limited by patient refusal. Conclusions The increase in CLABSIs in late 2020 during a surge in COVID-19 admissions was likely related to central line maintenance, but has resolved. Characterizing CLABSI cases can provide insight into adherence to guideline-recommended prevention practices and identify areas for improvement at individual institutions.

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Title: Subtitle: Descriptive Epidemiology of Central Line-Associated Bloodstream Infections at an Academic Medical Center in Iowa, 2019–2022
Creators: Elaine M. Harrington
Kathryn Trautman
Mary Beth Davis
Kristin Varzavand
Holly Meacham
Angelique Dains
Alexandre R. Marra
Jennifer McDanel
Lynnette Kenne
Beth Hanna
James P. Murphy
Daniel J. Diekema
Melanie Wellington
Karen B. Brust
Takaaki Kobayashi
Oluchi J. Abosi
Resource Type: Journal article
Publication Details: American journal of infection control, Vol.52(4), pp.436-442
DOI: 10.1016/j.ajic.2023.09.021
PMID: 37827243
NLM abbreviation: Am J Infect Control
ISSN: 0196-6553
eISSN: 1527-3296
Language: English
Electronic publication date: 10/2023
Date published: 04/2024
Academic Unit: Infectious Diseases; Stead Family Department of Pediatrics; Nursing; Infectious Disease (Pediatrics); Internal Medicine
Record Identifier: 9984476432902771

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