Descriptive Epidemiology of Orofacial Clefts in Ethiopia

Mekonen Eshete; Azeez Butali; Wakgari Deressa; Keyla Pagan-Rivera; Taye Hailu; Fikre Abate; Ibrahim Mohammed; Yohannes Demissie; Abiye Hailu; Deborah V Dawson; Milliard Deribew; Mulualem Gessese; Paul E Gravem; Peter Mossey

doi:10.1097/SCS.0000000000003234

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Descriptive Epidemiology of Orofacial Clefts in Ethiopia

Journal article

Peer reviewed

Descriptive Epidemiology of Orofacial Clefts in Ethiopia

Mekonen Eshete, Azeez Butali, Wakgari Deressa, Keyla Pagan-Rivera, Taye Hailu, Fikre Abate, Ibrahim Mohammed, Yohannes Demissie, Abiye Hailu, Deborah V Dawson, …

The Journal of craniofacial surgery, Vol.28(2), pp.334-337

03/2017

DOI: 10.1097/SCS.0000000000003234

PMCID: PMC5344734

PMID: 27984437

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https://discovery.dundee.ac.uk/en/publications/ff75e3e8-4302-4cd3-bca4-5409a220de26View

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Abstract

Background: The prevalence of birth defects including orofacial clefts (OFC) in Ethiopia is not known and there is no established birth defects registration system. Objectives: To investigate the prevalence and incidence of OFC in Ethiopia. Design: Retrospective hospital-based descriptive study. Methods: The authors obtained data from the Smile Train database on Ethiopian patients with OFC who underwent surgical treatment from June 2007 to December 2013 at 31 hospitals distributed throughout the country. Data related to live births in Ethiopia during the mentioned period were obtained from the Federal Ministry of Health database for estimates of the incidence and prevalence rates. Results: The total number of life births during the study period was 18,811,316. During this same period, 18,073 cleft patients approximately ranging from 1 to 75 years old were examined and treated at the hospitals mentioned earlier. The incidence rate estimated from the total number of affected children during the study period (N = 8232) is 0.44/1000 live births. The prevalence rate is 0.20/1000 and this was estimated using the number of total population in 2013 (N = 88,703,914). There is a significant difference in frequency between bilateral clefts of the lip and/or palate (CLP) (26.9%) versus unilateral CLP (73.1%) (P < 0.0001). There is also a significant difference in frequency between bilateral cleft lips only (15.4%) versus unilateral cleft lip only (84.6%), P < 0001. Conclusion: It is obvious that the findings in this study cannot be representative of the true picture but provides a previously unavailable national estimate of incidence and prevalence of OFC in Ethiopia. It can also be used as comparison for future community-based studies.

Epidemiology

Ethiopia

Cleft Palate

Cleft Lip

Cleft Lip and Palate

Details

Title: Subtitle: Descriptive Epidemiology of Orofacial Clefts in Ethiopia
Creators: Mekonen Eshete - School of Public Health, College of Health Sciences, Addis Ababa University, Addis, Ababa, Ethiopia
Azeez Butali - Department of Oral Pathology, Radiology and Medicine, College of Dentistry, University of Iowa, Iowa City, IA.U.S.A
Wakgari Deressa - School of Public Health, College of Health Sciences, Addis Ababa University, Addis, Ababa, Ethiopia
Keyla Pagan-Rivera - Division of Biostatistics and Research Design, College of Dentistry, University of Iowa
Taye Hailu - Yekatit 12 Hospital Medical College, Plastic and Reconstructive Surgery Unit, Addis Ababa, Ethiopia
Fikre Abate - Yekatit 12 Hospital Medical College, Plastic and Reconstructive Surgery Unit, Addis Ababa, Ethiopia
Ibrahim Mohammed - Department of Surgery, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia
Yohannes Demissie - Department of Surgery, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia
Abiye Hailu - Yekatit 12 Hospital Medical College, Plastic and Reconstructive Surgery Unit, Addis Ababa, Ethiopia
Deborah V Dawson - Division of Biostatistics and Research Design, College of Dentistry, University of Iowa
Milliard Deribew - Department of Surgery, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia
Mulualem Gessese - Yekatit 12 Hospital Medical College, Neonatology Unit, Addis Ababa, Ethiopia
Paul E Gravem - Haukeland University Hospital, Plastic and Reconstructive Surgery Department, Bergen, Norway
Peter Mossey - Department of Orthodontics, University of Dundee, Scotland, UK
Resource Type: Journal article
Publication Details: The Journal of craniofacial surgery, Vol.28(2), pp.334-337
DOI: 10.1097/SCS.0000000000003234
PMID: 27984437
PMCID: PMC5344734
NLM abbreviation: J Craniofac Surg
ISSN: 1049-2275
eISSN: 1536-3732
Language: English
Date published: 03/2017
Academic Unit: Oral Pathology, Radiology and Medicine; Stead Family Department of Pediatrics; Biostatistics; Pediatric Dentistry; Craniofacial Anomalies Research Center; Dental Research
Record Identifier: 9984065994502771

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