Journal article
Design, creation, and use of the Test Us Bank (TUB) COVID-19 sample biorepository
BMC infectious diseases, Vol.24(1), 1282
11/12/2024
DOI: 10.1186/s12879-024-10154-0
PMCID: PMC11556042
PMID: 39528968
Abstract
Shortly after the first case of SARS-CoV-2 was diagnosed a public health emergency (PHE) was declared and a multi-agency response was initiated within the US federal government to create and propagate testing capacity. As part of this response, an unprecedented program designated Rapid Acceleration of Diagnostics (RADx) Tech was established by the National Institutes of Health (NIH) to facilitate the development of point-of-care tests for the COVID-19. The RADx Tech Clinical Studies Core (CSC), located at the University of Massachusetts Chan Medical School (UMass Chan), with partnering academic, private, and non-governmental organizations around the country, was tasked with developing clinical studies to support this work. This manuscript details development of a biorepository specifically focused on the collection and storage of samples designed for diagnostic platform development. It highlights the unified collection and annotation process that enabled gathering a diverse set of samples. This diversity encompasses the geography and backgrounds of the participants as well as sample characteristics such as variant type and RT-PCR cycle threshold (CT) value of the corresponding reference sample on a uniform clinical reference platform.
Details
- Title: Subtitle
- Design, creation, and use of the Test Us Bank (TUB) COVID-19 sample biorepository
- Creators
- John Broach - University of Massachusetts Chan Medical SchoolChad Achenbach - Northwestern UniversityStephanie Behar - University of Massachusetts Chan Medical SchoolLaurel O’Connor - University of Massachusetts Chan Medical SchoolSeanan Tarrant - University of Massachusetts Chan Medical SchoolJulia Ferranto - University of Massachusetts Chan Medical SchoolColton Wright - University of Massachusetts Chan Medical SchoolPaul Hartin - University of Massachusetts Chan Medical SchoolTaylor Orwig - University of Massachusetts Chan Medical SchoolJanvi Nanavati - University of Massachusetts Chan Medical SchoolBenedict Kalibala - University of Massachusetts Chan Medical SchoolKelsey Woods - University of Massachusetts Chan Medical SchoolBernadette Shaw - University of Massachusetts Chan Medical SchoolJulie Flahive - University of Massachusetts Chan Medical SchoolBruce Barton - University of Massachusetts Chan Medical SchoolNathaniel Hafer - University of Massachusetts Chan Medical SchoolCarly Herbert - University of Massachusetts Chan Medical SchoolNisha Fahey - University of Massachusetts Chan Medical SchoolLaura Gibson - University of Massachusetts Chan Medical SchoolKarl Simin - University of Massachusetts Chan Medical SchoolTimothy Kowalik - University of Massachusetts Chan Medical SchoolDoyle V. Ward - University of Massachusetts Chan Medical SchoolAgha W. Mirza - Johns Hopkins MedicineRobert L. Murphy - Northwestern UniversityMatthew Caputo - Northwestern UniversityBryan Buchholz - University of Massachusetts LowellHeidi Fantasia - University of Massachusetts LowellAinat Koren - University of Massachusetts LowellLisa Marchand - University of Massachusetts LowellSimisola Oludare - Georgia Arrhythmia ConsultantsFelix Sogade - Georgia Arrhythmia ConsultantsDana Ritland - Marietta, GA USACedrice Davis - Marietta, GA USAAllen Grenier - University of Kansas Medical CenterChristi Baron - University of Kansas Medical CenterEllie Brent - University of Kansas Medical CenterJennifer Bacani McKenney - SUNY FredoniaNancy Elder - Oregon Health & Science UniversityLeAnn Michaels - Oregon Health & Science UniversityLaura Ferrara - Oregon Health & Science UniversityGrant Theron - South African Medical Research CouncilZaida Palmer - Stellenbosch UniversityBarcey Levy - University of Massachusetts Chan Medical SchoolJeanette Daly - University of Massachusetts Chan Medical SchoolKim Parang - University of Massachusetts Chan Medical SchoolMegan Schmidt - University of IowaDenis Buxton - National Institutes of HealthWilliam Heetderks - National Heart Lung and Blood InstituteYukari C. Manabe - Johns Hopkins MedicineApurv Soni - University of Massachusetts Chan Medical SchoolDavid McManus - University of Massachusetts Chan Medical School
- Resource Type
- Journal article
- Publication Details
- BMC infectious diseases, Vol.24(1), 1282
- Publisher
- BioMed Central
- DOI
- 10.1186/s12879-024-10154-0
- PMID
- 39528968
- PMCID
- PMC11556042
- ISSN
- 1471-2334
- eISSN
- 1471-2334
- Grant note
- National Heart, Lung, and Blood Institute of the National Institutes of Health: 3U54HL143541
Research reported in this manuscript was supported by National Heart, Lung, and Blood Institute of the National Institutes of Health under award number 3U54HL143541 .
- Language
- English
- Date published
- 11/12/2024
- Academic Unit
- Epidemiology; Family and Community Medicine; Community and Behavioral Health
- Record Identifier
- 9984748258702771
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