Journal article
Detecting of breast cancer metastasis by means of regional lymph node sampling during autologous; breast reconstruction - a screening of 519 consecutive patients
Medical science monitor, Vol.18(10), pp.CR605-CR610
10/01/2012
DOI: 10.12659/MSM.883486
PMCID: PMC3560567
PMID: 23018353
Abstract
Background: The internal mammary artery and vein is often used as a site of anastomoses in microvascular breast reconstruction. This area supports lymphatic drainage of the breast and its role in breast cancer metastasis remains unclear. We hypothesize that sampling of internal mammary lymph nodes at the time of microvascular anastomoses preparation may identify persistent or recurrent local disease and mandate the need for additional treatment in this area.
Material/Methods: A retrospective chart review from 519 patients in the time between January 2006 and September 2009 was performed on all patients who underwent internal mammary lymph node sampling at the time of microvascular breast reconstruction.
Results: Microvascular breast reconstruction was performed in 519 patients. Enlarged internal mammary lymph nodes were found and harvested in 195 patients for histological review. Six of 195 (3.08%) were found positive for metastatic disease requiring additional oncologic treatment.
Conclusion: The internal mammary lymphatic drainage system is an important and often underappreciated pathway for breast metastasis. Routine sampling of these lymph nodes at the time of microvascular breast reconstruction is easy to perform and is a useful tool to identify women, who might require additional treatment and increase cancer-free survival.
Details
- Title: Subtitle
- Detecting of breast cancer metastasis by means of regional lymph node sampling during autologous; breast reconstruction - a screening of 519 consecutive patients
- Creators
- Christoph Andree - Department of Plastic and Aesthetic Surgery, Interdisciplinary Breast Centre, Sana-Kliniken Düsseldorf, Gerresheim Hospital, Düsseldorf, GermanyVolker J. Schmidt - Friedrich-Alexander-Universität Erlangen-NürnbergBeatrix I. J. Munder - Gerresheim Hosp, Sana Kliniken Dusseldorf, Dept Plast & Aesthet Surg, Interdisciplinary Breast Ctr, D-40625 Dusseldorf, GermanyKatrin Seidenstuecker - Gerresheim Hosp, Sana Kliniken Dusseldorf, Dept Plast & Aesthet Surg, Interdisciplinary Breast Ctr, D-40625 Dusseldorf, GermanyPhilipp Behrendt - Department of Plastic and Aesthetic Surgery, Interdisciplinary Breast Centre, Sana-Kliniken Düsseldorf, Gerresheim Hospital, Düsseldorf, GermanyChristian Witzel - Department of Plastic and Aesthetic Surgery, Interdisciplinary Breast Centre, Sana-Kliniken Düsseldorf, Gerresheim Hospital, Düsseldorf, GermanyRaymund E. Horch - Friedrich-Alexander-Universität Erlangen-NürnbergBrian T. Andrews - Brigham and Women's HospitalPhilipp Richrath - Department of Plastic and Aesthetic Surgery, Interdisciplinary Breast Centre, Sana-Kliniken Düsseldorf, Gerresheim Hospital, Düsseldorf, Germany
- Resource Type
- Journal article
- Publication Details
- Medical science monitor, Vol.18(10), pp.CR605-CR610
- DOI
- 10.12659/MSM.883486
- PMID
- 23018353
- PMCID
- PMC3560567
- NLM abbreviation
- Med Sci Monit
- ISSN
- 1643-3750
- eISSN
- 1643-3750
- Publisher
- Int Scientific Information, Inc
- Number of pages
- 6
- Language
- English
- Date published
- 10/01/2012
- Academic Unit
- Craniofacial Anomalies Research Center; Neurosurgery; Otolaryngology
- Record Identifier
- 9984366282202771
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