Journal article
Detection and quantitation of human immunodeficiency virus type 1 using molecular DNA/RNA technology
Archives of pathology & laboratory medicine (1976), Vol.117(5), pp.473-477
05/1993
PMID: 8489334
Abstract
The direct detection and quantitation of human immunodeficiency virus type 1 are becoming increasingly important for diagnosis and viral load determinations in human immunodeficiency virus type 1 infection. Traditional molecular-based assays such as Southern, Northern, and in situ hybridization have had limited application in this area due to the relatively low number of proviral copies per cell, the low percentage of infected cells, and transcriptional dormancy in many of the infected cells. Recent technological advances in polymerase chain reaction assays promise a number of useful applications in the clinical research and clinical laboratory setting.
Details
- Title: Subtitle
- Detection and quantitation of human immunodeficiency virus type 1 using molecular DNA/RNA technology
- Creators
- J B Jackson - Institute of Pathology, Case Western Reserve University, University Hospitals of Cleveland, Ohio
- Resource Type
- Journal article
- Publication Details
- Archives of pathology & laboratory medicine (1976), Vol.117(5), pp.473-477
- Publisher
- United States
- PMID
- 8489334
- ISSN
- 0003-9985
- eISSN
- 1543-2165
- Language
- English
- Date published
- 05/1993
- Academic Unit
- Pathology; VPMA - Administration
- Record Identifier
- 9984047792902771
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