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Determining a detectable threshold of signal intensity in cDNA microarray based on accumulated distribution
Journal article   Open access   Peer reviewed

Determining a detectable threshold of signal intensity in cDNA microarray based on accumulated distribution

Xia Gao, Xuping Fu, Tao Li, Jian Zi, Yao Luo, Qing Wei, Erliang Zeng, Yi Xie, Yao Li and Yumin Mao
Journal of biochemistry and molecular biology, Vol.36(6), pp.558-564
11/30/2003
DOI: 10.5483/BMBRep.2003.36.6.558
PMID: 14659074
url
https://doi.org/10.5483/BMBRep.2003.36.6.558View
Published (Version of record) Open Access

Abstract

In microarray data mining, one of the key problems is how to handle weak signals. Based on a bent piecewise linear accumulated distribution generally found in the microarray data, a new detectable threshold finding method is proposed to filter genes with unreliable information in this paper. More reliable and reproducible data is produced for the subsequent data mining.
Oligonucleotide Array Sequence Analysis Reproducibility of Results DNA, Complementary - genetics

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