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Determining the Presence of Superantigens in Coagulase Negative Staphylococci from Humans
Journal article   Open access   Peer reviewed

Determining the Presence of Superantigens in Coagulase Negative Staphylococci from Humans

Christopher S Stach, Bao G Vu and Patrick M Schlievert
PloS one, Vol.10(11), pp.e0143341-e0143341
2015
DOI: 10.1371/journal.pone.0143341
PMCID: PMC4658126
PMID: 26599862
url
https://doi.org/10.1371/journal.pone.0143341View
Published (Version of record) Open Access

Abstract

Superantigens (SAgs) are important virulence factors in S. aureus. Recent studies identified their presence in animal coagulase-negative staphylococci (CNS). The emergence of human-associated SAg+ CNS would mark a prodigious shift in virulence capabilities. We examined CNS isolates from healthy human nares and diseased individuals, and determined that no known SAgs were present.
Staphylococcus aureus - isolation & purification Humans Staphylococcus aureus - immunology Virulence Factors - analysis Virulence Factors - immunology Superantigens - immunology Healthy Volunteers Superantigens - analysis

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