Journal article
Development and Validation of a Short Portable Sarcopenia Measure in the African American Health Project
The journals of gerontology. Series A, Biological sciences and medical sciences, Vol.64(3), pp.388-394
03/01/2009
DOI: 10.1093/gerona/gln033
PMCID: PMC2655004
PMID: 19181712
Abstract
Poor muscle size and function (sarcopenia) have an important role in the age-associated disability process. However, no commonly accepted index of sarcopenia exists for use in epidemiological studies.
A cohort of 998 community-dwelling African Americans 49-65 years' old at baseline was used to construct the short portable sarcopenia measure (SPSM). SPSM was conceptualized as a measure of sarcopenia that combines estimates of muscle quantity and function into a single scale, is based on component items that can be obtained easily in the field, represents muscle status at a single time point that can be used without sex-specific adjustments, and can be used to follow change in muscle status over time with each person as his or her own control. We used exploratory factor analysis (EFA) to identify a unidimensional scale based on timed chair rises, lean mass, and grip strength divided by height. We used these three items and their EFA factor weights to construct SPSM (mean 9.0, median 9, range 0 [worst] to 18 [best] at baseline). Construct validity of the new measure, over a period of 36 months was examined.
SPSM required 8.5 pounds of equipment and 12.4 minutes to complete. It showed good score distribution and convergent, discriminant, and predictive validity with measures of muscle function, body composition, physical performance, psychological factors, and functional limitation cross-sectionally and with muscle function and body composition longitudinally. Extensive sensitivity analyses confirmed SPSM's robustness.
SPSM is a brief, portable, and valid measure of sarcopenia for use in epidemiological research. Similar studies in other populations are needed.
Details
- Title: Subtitle
- Development and Validation of a Short Portable Sarcopenia Measure in the African American Health Project
- Creators
- Douglas K. Miller - Indiana UniversityTheodore K. Malmstrom - Saint Louis UniversityElena M. Andresen - University of FloridaJ. Philip Miller - Washington University in St. Louis School of MedicineMargaret M. Herning - Saint Louis UniversityMario Schootman - Washington University in St. LouisFredric D. Wolinsky - University of Iowa
- Resource Type
- Journal article
- Publication Details
- The journals of gerontology. Series A, Biological sciences and medical sciences, Vol.64(3), pp.388-394
- DOI
- 10.1093/gerona/gln033
- PMID
- 19181712
- PMCID
- PMC2655004
- NLM abbreviation
- J Gerontol A Biol Sci Med Sci
- ISSN
- 1079-5006
- eISSN
- 1758-535X
- Publisher
- Oxford Univ Press
- Number of pages
- 7
- Grant note
- R01 AG-10436; R01 AG010436 / NIA NIH HHS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute on Aging (NIA) R01AG010436 / NATIONAL INSTITUTE ON AGING; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute on Aging (NIA)
- Language
- English
- Date published
- 03/01/2009
- Academic Unit
- Health Management and Policy
- Record Identifier
- 9984363595102771
Metrics
8 Record Views