Journal article
Development of a novel linearly-filled Derenzo microPET phantom
American journal of nuclear medicine and molecular imaging, Vol.6(3), pp.199-204
01/01/2016
PMCID: PMC4965524
PMID: 27508106
Abstract
Positron emission tomography (PET) phantoms are used to calibrate PET scanners so that inter-scanner and inter-isotope comparison can be made between PET datasets. Hot rod style phantoms have a hole pattern, which is filled with a positron-emitting isotope and typically involves using two radioisotope reservoirs with the pattern created with channels in between. However, this configuration is difficult to fill and requires an excess of activity and volume. Here we present an alternative design, a phantom that is linearly filled-one channel at a time. The process of fabrication of prototypes of the design is described and PET images of the prototyped phantom are also shown for a variety of commonly used radioisotopes (
52
Mn,
64
Cu,
76
Br,
124
I). This design allows for a large reduction in isotope volume and required filling time making a quality assurance (QA) protocol safer, more efficient and less costly.
Details
- Title: Subtitle
- Development of a novel linearly-filled Derenzo microPET phantom
- Creators
- Benjamin L Cox - Morgridge Institute for ResearchStephen A Graves - Department of Medical Physics, University of WisconsinMohammed Farhoud - Sofie BiosciencesTodd E Barnhart - Department of Medical Physics, University of WisconsinJustin J Jeffery - University of Wisconsin Carbone Cancer CenterKevin W Eliceiri - University of Wisconsin Carbone Cancer CenterRobert J Nickles - Department of Medical Physics, University of Wisconsin
- Resource Type
- Journal article
- Publication Details
- American journal of nuclear medicine and molecular imaging, Vol.6(3), pp.199-204
- Publisher
- e-Century Publishing Corporation
- PMID
- 27508106
- PMCID
- PMC4965524
- ISSN
- 2160-8407
- eISSN
- 2160-8407
- Language
- English
- Date published
- 01/01/2016
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Radiology; Radiation Oncology
- Record Identifier
- 9984384333502771
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