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Development of the zebrafish inner ear
Journal article   Open access   Peer reviewed

Development of the zebrafish inner ear

Tanya T Whitfield, Bruce B Riley, Ming‐Yung Chiang and Bryan Phillips
Developmental dynamics, Vol.223(4), pp.427-458
04/2002
DOI: 10.1002/dvdy.10073
PMID: 11921334
url
https://doi.org/10.1002/dvdy.10073View
Published (Version of record) Open Access

Abstract

Recent years have seen a renaissance of investigation into the mechanisms of inner ear development. Genetic analysis of zebrafish has contributed significantly to this endeavour, with several dramatic advances reported over the past year or two. Here, we review the major findings from recent work in zebrafish. Several cellular and molecular mechanisms have been elucidated, including the signaling pathways controlling induction of the otic placode, morphogenesis and patterning of the otic vesicle, and elaboration of functional attributes of inner ear. © 2002 Wiley‐Liss, Inc.
acerebellar auditory balance BMP cell death Claudins colourless Dach deafness Delta‐Notch dog‐eared ear Eya1 FGF hair cell hearing jekyll Krml1 lateral line mariner mind bomb monolith MyoVIIa neckless Nkx5.1 no fin no isthmus one‐eyed pinhead otic placode otic vesicle Pax2/5/8 Pou2 Raldh2 retinoic acid Sox10 spiel ohne grenzen sputnik statoacoustic ganglion supporting cell Ugdh valentino van gogh vestibular Wnt zebrafish

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