Journal article
Developmental outcomes of extremely preterm infants born to adolescent mothers
Pediatrics (Evanston), Vol.135(6), pp.1082-1092
06/2015
DOI: 10.1542/peds.2014-3880
PMCID: PMC4444804
PMID: 25963007
Abstract
Extremely preterm infants and infants born to adolescent mothers are at risk for adverse developmental. The objectives were to evaluate development and behavior outcomes of extremely low birth weight (ELBW) infants born to adolescent mothers <20 compared with adult mothers ≥20 years and to identify socioeconomic risk factors that affect outcomes.
Retrospective cohort analysis of 211 infants >27 weeks of adolescent mothers and 1723 infants of adult mothers at Neonatal Research Network centers from 2008 to 2011. Groups were compared and regression models were run to predict 18- to 22-month adverse outcomes. Primary outcomes were Bayley-III scores, neurodevelopmental impairment, and Brief Infant Toddler Social Emotional Assessment problem scores (BITSEA/P) ≥75th percentile.
Adolescent mothers were more often single, Hispanic, less educated, and had public insurance. By 18 to 22 months, their children had significantly increased rates of having lived ≥3 places (21% vs 9%), state supervision (7% vs 3%), rehospitalization (56% vs 46%), and BITSEA/P ≥75th percentile (50% vs 32%) and nonsignificant Bayley-III language scores <85 (56% vs 49%, P = .07). In regression analysis, children of adolescent mothers were more likely to have BITSEA/P ≥75th percentile (relative risk 1.50, 95% confidence interval 1.08-2.07). Living ≥3 places and nonwhite race were predictors of adverse behavior. State supervision was an independent predictor of each Bayley-III composite <70 and neurodevelopmental impairment.
ELBW infants of adolescent mothers experience high social and environmental risks that are associated with adverse behavior outcomes. These findings inform the need for comprehensive follow-up, coordinated care services, and behavior interventions for ELBW infants of adolescent mothers.
Details
- Title: Subtitle
- Developmental outcomes of extremely preterm infants born to adolescent mothers
- Creators
- Laurie Hoffman - Women & Infants Hospital of Rhode IslandCarla Bann - RTI InternationalRosemary Higgins - Eunice Kennedy Shriver National Institute of Child Health and Human DevelopmentBetty Vohr - Women & Infants Hospital of Rhode IslandEunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network
- Contributors
- Tarah T Colaizy (Contributor) - University of Iowa, NeonatologyEdward F Bell (Contributor) - University of Iowa, Neonatology
- Resource Type
- Journal article
- Publication Details
- Pediatrics (Evanston), Vol.135(6), pp.1082-1092
- DOI
- 10.1542/peds.2014-3880
- PMID
- 25963007
- PMCID
- PMC4444804
- NLM abbreviation
- Pediatrics
- ISSN
- 0031-4005
- eISSN
- 1098-4275
- Grant note
- U10 HD053124 / NICHD NIH HHS UG1 HD053089 / NICHD NIH HHS U10 HD053119 / NICHD NIH HHS U10 HD027871 / NICHD NIH HHS M01 RR008084 / NCRR NIH HHS UG1 HD027880 / NICHD NIH HHS U10 HD021373 / NICHD NIH HHS U10 HD040492 / NICHD NIH HHS U10 HD068244 / NICHD NIH HHS U10 HD036790 / NICHD NIH HHS UL1 RR024139 / NCRR NIH HHS U10 HD040521 / NICHD NIH HHS U10 HD068270 / NICHD NIH HHS U10 HD053089 / NICHD NIH HHS U10 HD040689 / NICHD NIH HHS U10 HD027904 / NICHD NIH HHS U10 HD053109 / NICHD NIH HHS U10 HD027856 / NICHD NIH HHS U10 HD027880 / NICHD NIH HHS U10 HD027853 / NICHD NIH HHS U10 HD021364 / NICHD NIH HHS U10 HD068284 / NICHD NIH HHS U10 HD068278 / NICHD NIH HHS U10 HD027851 / NICHD NIH HHS U10 HD034216 / NICHD NIH HHS U10 HD021385 / NICHD NIH HHS U10 HD068263 / NICHD NIH HHS UG1 HD034216 / NICHD NIH HHS U10 HD040461 / NICHD NIH HHS UG1 HD021364 / NICHD NIH HHS
- Language
- English
- Date published
- 06/2015
- Academic Unit
- Stead Family Department of Pediatrics; Neonatology
- Record Identifier
- 9984353929002771
Metrics
9 Record Views