Journal article
Diabetes as an increasingly common comorbidity among patient hospitalizations for tuberculosis in the USA
BMJ open diabetes research & care, Vol.4(1), p.e000268
2016
DOI: 10.1136/bmjdrc-2016-000268
PMCID: PMC5073569
PMID: 27843553
Abstract
OBJECTIVE: Diabetes is a risk factor for active tuberculosis (TB). The purpose of this paper was to estimate the risk of hospitalization for TB with and without a secondary diagnosis of diabetes in groups with different ethnic backgrounds.RESEARCH DESIGN AND METHODS: We used the Nationwide Inpatient Sample from 1998 to 2011, identifying all patients with a primary diagnosis of TB and/or a secondary diagnosis of diabetes (type 1 or type 2) or HIV. Next, we performed logistic regression to investigate the association of diabetes status, HIV status, and race (and the interaction of diabetes and race) with the risk of hospitalization with a primary diagnosis of TB. We also included a time covariate, to determine whether potential risk factors changed during the study period.RESULTS: Controlling for HIV status, diabetes did not increase the odds of TB in white and black patients. However, in Hispanic and Asian/Pacific Islander patients, diabetes increased the odds of TB by a factor of 1.7 (95% CI 1.51 to 1.83). Asian/Pacific Islanders who had diabetes but not HIV experienced 26.4 (95% CI 23.1 to 30.1) times the odds of TB relative to the white males without diabetes or HIV. In addition, the percent of TB cases that belong to these high-risk groups (Asian/Pacific Islander/Hispanic diabetics) has more than doubled from 4.6% in 1998 to 9.6% in 2011.CONCLUSIONS: In specific demographic groups, diabetes was a strong risk factor for hospital admissions for TB.
Details
- Title: Subtitle
- Diabetes as an increasingly common comorbidity among patient hospitalizations for tuberculosis in the USA
- Creators
- Roula S ZahrRyan A PetersonLinnea A PolgreenJoseph E CavanaughDouglas B HornickKevin L WinthropPhilip M Polgreen
- Resource Type
- Journal article
- Publication Details
- BMJ open diabetes research & care, Vol.4(1), p.e000268
- DOI
- 10.1136/bmjdrc-2016-000268
- PMID
- 27843553
- PMCID
- PMC5073569
- NLM abbreviation
- BMJ Open Diabetes Res Care
- ISSN
- 2052-4897
- eISSN
- 2052-4897
- Language
- English
- Date published
- 2016
- Academic Unit
- Statistics and Actuarial Science; Pulmonary, Critical Care, and Occupational Medicine; Infectious Diseases; Epidemiology; Economics; Biostatistics; Pharmacy Practice and Science; Injury Prevention Research Center; Internal Medicine
- Record Identifier
- 9983985893102771
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