Journal article
Diabetic Retinopathy
The New England journal of medicine, Vol.367(2), pp.184-184
07/12/2012
DOI: 10.1056/NEJMc1205011
PMID: 22784133
Abstract
To the Editor:
In their review article on diabetic retinopathy (March 29 issue),
1
Antonetti et al. describe the retinal dysfunction associated with diabetes as “a change in the retinal neurovascular unit,” alluding to energy homeostasis, but do not refer to the article by Arden.
2
In this article, Arden points out that the 120 million rods have the highest metabolic rate of any cell, requiring a great deal of energy and oxygen, especially in the dark.
3
Since the rods are avascular, the partial pressure of oxygen among the mitochondria is essentially zero. Thus, in dark adaptation, the retina uses so much . . .
Details
- Title: Subtitle
- Diabetic Retinopathy
- Creators
- Panagis Drakatos - Guy's and St. Thomas' NHS Foundation Trust, London, United KingdomChristopher Kosky - Guy's and St. Thomas' NHS Foundation Trust, London, United KingdomAdrian J Williams - Guy's and St. Thomas' NHS Foundation Trust, London, United KingdomRajesh C Rao - Washington University School of Medicine, St. Louis, MOBrian J Dlouhy - University of Iowa Hospitals and Clinics, Iowa City, IA
- Resource Type
- Journal article
- Publication Details
- The New England journal of medicine, Vol.367(2), pp.184-184
- Publisher
- Massachusetts Medical Society
- DOI
- 10.1056/NEJMc1205011
- PMID
- 22784133
- ISSN
- 0028-4793
- eISSN
- 1533-4406
- Language
- English
- Date published
- 07/12/2012
- Academic Unit
- Stead Family Department of Pediatrics; Iowa Neuroscience Institute; Neurosurgery
- Record Identifier
- 9984070335102771
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