Logo image
Diagnosis and outcome in schizo-affective depression: A replication
Journal article   Peer reviewed

Diagnosis and outcome in schizo-affective depression: A replication

William Coryell and Mark Zimmerman
Journal of affective disorders, Vol.15(1), pp.21-27
1988
DOI: 10.1016/0165-0327(88)90005-5
PMID: 2970489

View Online

Abstract

Forty-three inpatients with RDC schizo-affective depression were given structured interviews and then followed to 1 year using a design closely resembling that of another recent follow-up of schizo-affective patients. In replication of the earlier study, patients with either ‘chronic’ or ‘mainly schizophrenic’ schizo-affective disorder had significantly worse outcomes than did patients with nonchronic or ‘mainly affective’ schizo-affective depression and bipolar patients were significantly more likely to develop manic syndromes. The preceding duration of schizophrenia-like symptoms and a history of schizophrenia-like prodomes appeared to be the most important components of these two distinctions. In both studies, diagnostic subtype was the most robust of various potential outcome predictors. Also in both studies, ‘mainly affective’ and ‘nonchronic’ schizo-affective patients had outcomes no different from patients with psychotic depression.
Schizo-affective depression Replication Follow-up

Details

Metrics

Logo image