Journal article
Diagnosis of Helicobacter pylori infection
Gastroenterology clinics of North America, Vol.22(1), pp.105-115
03/1993
PMID: 8449560
Abstract
In conclusion, H. pylori infection can be detected by a variety of methods. The simplest, least expensive noninvasive method is serologic testing. Unfortunately, positive serology can only presume current infection. Urea breath testing is also noninvasive and is positive only in the setting of current infection; it is more expensive than serology and results in low-level radiation exposure when 14C urea is used. Endoscopy with biopsy is invasive and relatively expensive; however, it is readily available and is frequently performed in the evaluation of the symptomatic individual. In such cases, rapid urease testing of biopsy material is simple and less expensive than histologic examination. Histology allows simultaneous evaluation of tissue injury and infection. Frequently, routine hematoxylin-and-eosin staining is sufficient to permit identification of the bacteria; when the results of this stain are inconclusive, special stains such as Giemsa or Warthin-Starry can be used. Finally, direct culture of the organism from gastric tissue is tedious and expensive; therefore, it should generally be reserved for protocol settings or for selected patients in whom antibiotic-resistant organisms are suspected.
Details
- Title: Subtitle
- Diagnosis of Helicobacter pylori infection
- Creators
- K E Brown - Division of Gastroenterology, University of Virginia Health Sciences Center, CharlottesvilleD A Peura
- Resource Type
- Journal article
- Publication Details
- Gastroenterology clinics of North America, Vol.22(1), pp.105-115
- Publisher
- United States
- PMID
- 8449560
- ISSN
- 0889-8553
- eISSN
- 1558-1942
- Language
- English
- Date published
- 03/1993
- Academic Unit
- Gastroenterology and Hepatology; Radiation Oncology; Internal Medicine
- Record Identifier
- 9984047876902771
Metrics
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