Journal article
Diagnosis of fetal infections
Current opinion in obstetrics & gynecology, Vol.16(2), pp.163-166
04/2004
DOI: 10.1097/00001703-200404000-00012
PMID: 15017347
Abstract
The purpose of this review is to present recent developments in the prenatal diagnosis of the most clinically relevant congenital infections.
Immunoglobin G avidity testing can help to differentiate between recent or prior infection. A combination of tests, including serology, avidity and polymerase chain reaction, may be necessary to improve accuracy of diagnosis. The interval between exposure to an infectious agent and prenatal testing can be critical to the interpretation of the test result.
This review reinforces the need for accurate testing to guide appropriate counseling and individual fetal risk assessment. The findings of viral-specific antibodies or sonographic abnormalities do not accurately predict the severity or outcome of fetal infection. Further research is necessary to determine the pathogenesis of transplacental viral transmission and thereby allow us to target prevention strategies.
Details
- Title: Subtitle
- Diagnosis of fetal infections
- Creators
- Janet I Andrews - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Current opinion in obstetrics & gynecology, Vol.16(2), pp.163-166
- DOI
- 10.1097/00001703-200404000-00012
- PMID
- 15017347
- ISSN
- 1040-872X
- eISSN
- 1473-656X
- Language
- English
- Date published
- 04/2004
- Academic Unit
- Obstetrics and Gynecology
- Record Identifier
- 9984696760602771
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