Diagnostic criteria for vascular cognitive disorders: a VASCOG statement

Perminder Sachdev; Raj Kalaria; John O’Brien; Ingmar Skoog; Suvarna Alladi; Sandra E Black; Deborah Blacker; Dan Blazer; Christopher Chen; Helena Chui; Mary Ganguli; Kurt Jellinger; Dilip V Jeste; Florence Pasquier; Jane Paulsen; Niels Prins; Kenneth Rockwood; Gustavo Roman; Philip Scheltens; Internationlal Society for Vascular Behavioral and Cognitive Disorders

doi:10.1097/WAD.0000000000000034

Journal article

Diagnostic criteria for vascular cognitive disorders: a VASCOG statement

Perminder Sachdev, Raj Kalaria, John O’Brien, Ingmar Skoog, Suvarna Alladi, Sandra E Black, Deborah Blacker, Dan Blazer, Christopher Chen, Helena Chui, …

Alzheimer disease and associated disorders, Vol.28(3), pp.206-218

2014

DOI: 10.1097/WAD.0000000000000034

PMCID: PMC4139434

PMID: 24632990

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Abstract

Background: Several sets of diagnostic criteria have been published for vascular dementia since the 1960s. The continuing ambiguity in vascular dementia definition warrants a critical reexamination. Methods: Participants at a special symposium of the International Society for Vascular Behavioral and Cognitive Disorders (VASCOG) in 2009 critiqued the current criteria. They drafted a proposal for a new set of criteria, later reviewed through multiple drafts by the group, including additional experts and the members of the Neurocognitive Disorders Work Group of the fifth revision of Diagnostic and Statistical Manual (DSM-5) Task Force. Results: Cognitive disorders of vascular etiology are a heterogeneous group of disorders with diverse pathologies and clinical manifestations, discussed broadly under the rubric of vascular cognitive disorders (VCD). The continuum of vascular cognitive impairment is recognized by the categories of Mild Vascular Cognitive Disorder, and Vascular Dementia or Major Vascular Cognitive Disorder. Diagnostic thresholds are defined. Clinical and neuroimaging criteria are proposed for establishing vascular etiology. Subtypes of VCD are described, and the frequent cooccurrence of Alzheimer disease pathology emphasized. Conclusions: The proposed criteria for VCD provide a coherent approach to the diagnosis of this diverse group of disorders, with a view to stimulating clinical and pathologic validation studies. These criteria can be harmonized with the DSM-5 criteria such that an international consensus on the criteria for VCD may be achieved.

diagnostic criteria

Vascular dementia

cerebrovascular disease

vascular cognitive impairment

subcortical dementia

multi-infarct dementia

post-stroke dementia

vascular cognitive disorder

Details

Title: Subtitle: Diagnostic criteria for vascular cognitive disorders: a VASCOG statement
Creators: Perminder Sachdev - Neuropsychiatry, School of Psychiatry, University of New South Wales, Sydney, Australia
Raj Kalaria - Cerebrovascular Pathology (Neuropathology), Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle-Upon-Tyne NE4 5PL, United Kingdom
John O’Brien - Old Age Psychiatry, Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle NE4 5PL, UK
Ingmar Skoog - Social Psychiatry and Epidemiology, Neuropsykiatri SU/M�lndal, Wallinsgatan 6, 431 41 M�lndal, Sweden
Suvarna Alladi - Department of Neurology, Nizam's Institute of Medical Sciences, Hyderabad, India
Sandra E Black - Neurology, University of Toronto, Sunnybrook Health Sciences Centre, Room A421- 2075 Bayview Avenue, Toronto, ON M4N 3M5
Deborah Blacker - Psychiatry, Harvard Medical School, Boston Mass., USA
Dan Blazer - Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina 27710, USA
Christopher Chen - Memory Aging and Cognition Centre, National University Health System, Kent Ridge Road, Singapore 119228
Helena Chui - Department of Neurology, University of Southern California, Keck School of Medicine, Los Angeles, CA, USA
Mary Ganguli - Psychiatry, Neurology, and Epidemiology, University of Pittsburgh School of Medicine and Graduate School of Public Health, Pittsburgh, USA
Kurt Jellinger - Institute of Clinical Neurobiology, Kenyongasse 18; A-1070 Vienna
Dilip V Jeste - Estelle and Edgar Levi Chair in Aging and Distinguished Professor of Psychiatry and Neurosciences, University of California, San Diego, California 92093, USA
Florence Pasquier - University Lille Nord de France UDSL and Memory Clinic, CHU, 59000 Lille, France
Jane Paulsen - Psychiatry, Neurology, Psychology and Neurosciences, The Carver College of Medicine, The University of Iowa, Iowa City, IA 52242, USA
Niels Prins - Alzheimer Centre and Department of Neurology, VU University Medical Centre, Amsterdam, the Netherlands
Kenneth Rockwood - Medicine (Geriatric Medicine & Neurology) and Kathryn Allen Weldon Professor of Alzheimer Research, Dalhousie University Halifax NS Canada B3H 2E1
Gustavo Roman - Jack S. Blanton Distinguished Chair, Director Nantz National Alzheimer Center, Methodist Neurological Institute, 6560 Fannin Street, Suite 802, Houston, Texas 77030, USA
Philip Scheltens - Alzheimer Centre and Department of Neurology, VU University Medical Centre, Amsterdam, the Netherlands
Internationlal Society for Vascular Behavioral and Cognitive Disorders
Resource Type: Journal article
Publication Details: Alzheimer disease and associated disorders, Vol.28(3), pp.206-218
DOI: 10.1097/WAD.0000000000000034
PMID: 24632990
PMCID: PMC4139434
NLM abbreviation: Alzheimer Dis Assoc Disord
ISSN: 0893-0341
eISSN: 1546-4156
Language: English
Date published: 2014
Academic Unit: Psychiatry; Psychological and Brain Sciences
Record Identifier: 9984083292502771

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