Journal article
Diagnostic performance of contrast-enhanced and unenhanced combined pulmonary artery MRI and magnetic resonance venography techniques in the diagnosis of venous thromboembolism
British journal of radiology, Vol.92(1095), 20180695
03/2019
DOI: 10.1259/bjr.20180695
PMCID: PMC6541198
PMID: 30629460
Abstract
We aimed to determine the diagnostic performance of the contrast-enhanced and unenhanced combined pulmonary arterial MRI and magnetic resonance venography techniques in the diagnosis of venous thromboembolism (VTE).
Methods:
44 patients who underwent CT pulmonary angiography (CTPA) for suspected PE constituted the study population. Patients underwent combined pulmonary and lower extremity MRI, and Doppler ultrasonography within 72 h after CTPA. Combined MRI included two sequences: unenhanced steady-state free precession (SSFP) and contrast-enhanced three-dimensional (3D) gradient echo (GRE). The presence of emboli in pulmonary arteries and thrombi in lower extremity veins on 3D-GRE and SSFP sequences was recorded.
Results:
CTPA showed a total of 244 emboli in 33 (75%) patients whereas contrast-enhanced 3D-GRE MRI showed deep vein thrombosis (DVT) in 34 (77%) subjects. Sensitivities for SSFP vs 3D-GRE MRI respectively in PE detection were 87.9 vs 100% on a per-patient basis, and 53.7 vs 73% on a per-embolus basis. Of 34 patients with established DVT, 31 (91%) were detected by Doppler ultrasound and 29 (85%) were detected by SSFP technique respectively.
Conclusion:
Both contrast-enhanced and unenhanced combined MRI of acute PE and DVT are feasible one-stop-shopping techniques in patients with suspected thromboembolism.
Advances in knowledge:
Pulmonary VTE is a common disease with high mortality. Non-invasive techniques withhigh accuracy are required for the assessment of VTE. CT-related radiation and contrast material risks cause concerns. MRI is a radiation-free technique evaluating the vessels with and without contrast. Combined contrast enhancedor unenhanced pulmonary and lower extremity MRI is feasible in patients with suspected thromboembolism.
Details
- Title: Subtitle
- Diagnostic performance of contrast-enhanced and unenhanced combined pulmonary artery MRI and magnetic resonance venography techniques in the diagnosis of venous thromboembolism
- Creators
- Furkan Kaya - Usak UniversityFurkan Ufuk - Pamukkale UniversityNevzat Karabulut - Denizli Devlet Hastanesi
- Resource Type
- Journal article
- Publication Details
- British journal of radiology, Vol.92(1095), 20180695
- Publisher
- The British Institute of Radiology
- DOI
- 10.1259/bjr.20180695
- PMID
- 30629460
- PMCID
- PMC6541198
- ISSN
- 0007-1285
- eISSN
- 1748-880X
- Alternative title
- Full paper: Combined pulmonary artery MRI and magnetic resonance venography
- Language
- English
- Date published
- 03/2019
- Academic Unit
- Radiology
- Record Identifier
- 9984697633202771
Metrics
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