Journal article
Diet and risk of non-Hodgkin lymphoma in older women
JAMA : the journal of the American Medical Association, Vol.275(17), pp.1315-1321
05/01/1996
DOI: 10.1001/jama.275.17.1315
PMID: 8614116
Abstract
Objective.-To test whether high dietary intakes of fat, protein, and milk are associated with the development of non-Hodgkin lymphoma in older women.
Design.-Prospective cohort study with a 7-year follow-up period.
Setting.-General community.
Participants.-Sample of 35 156 Iowa women aged 55 to 69 years with no prior history of cancer who returned the 1986 baseline questionnaire.
Main Outcome Measure.-Non-Hodgkin lymphoma (104 incident cases).
Main Results.-After controlling for age, marital status, residence, total energy intake, and transfusion history, the relative risks (RRs) for the highest tertile of intake compared with the lowest were 2.00 (95% confidence interval [CI], 1.21-3.30; P for trend=.01) for animal fat, 1.69 (95% CI, 1.07-2.67; P for trend=.02) for saturated fat, and 1.90 (95% CI, 1.18-3.04; P for trend=.01) for monounsaturated fat, and there was no association with vegetable fat or polyunsaturated fat. Greater intake of animal protein (RR=1.52; 95% CI, 0.94-2.44; P for trend=.08), but not vegetable protein, was associated with elevated risk, and this was mainly explained by greater consumption of red meat (RR=1.98; 95% CI, 1.13-3.47; P for trend=.02) and hamburger in particular (RR=2.35; 95% CI, 1.23-4.48; P for trend=.02). Milk and dairy product consumption were not associated with elevated risk. There was also a decreased risk of non-Hodgkin lymphoma with greater consumption of fruits (RR=0.64; 95% CI, 0.40-1.05; P for trend=.07).
Conclusions.-A high-meat diet and a high intake of fat from animal sources is associated with an increased risk of non-Hodgkin lymphoma in older women.
Details
- Title: Subtitle
- Diet and risk of non-Hodgkin lymphoma in older women
- Creators
- Brian C H Chiu - University of IowaJames R Cerhan - University of IowaAaron R FolsomThomas A SellersLawrence H KushiRobert B Wallace - University of IowaWei ZhengJohn D Potter
- Resource Type
- Journal article
- Publication Details
- JAMA : the journal of the American Medical Association, Vol.275(17), pp.1315-1321
- DOI
- 10.1001/jama.275.17.1315
- PMID
- 8614116
- NLM abbreviation
- JAMA
- ISSN
- 0098-7484
- eISSN
- 1538-3598
- Publisher
- Amer Medical Assoc
- Number of pages
- 7
- Grant note
- R01 CA39742 / NCI NIH HHS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI) R01CA039742 / NATIONAL CANCER INSTITUTE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI)
- Language
- English
- Date published
- 05/01/1996
- Academic Unit
- Epidemiology; Injury Prevention Research Center; Internal Medicine
- Record Identifier
- 9984363610902771
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