Dietary inflammatory index and cardiovascular disease risk in Hispanic women from the Women's Health Initiative

Monica D Zuercher; Danielle J Harvey; Margarita Santiago-Torres; Lauren E Au; Nitin Shivappa; Aladdin H Shadyab; Matthew Allison; Linda Snetselaar; Buyun Liu; John A Robbins; James R Hébert; Lorena Garcia

doi:10.1186/s12937-023-00838-9

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Dietary inflammatory index and cardiovascular disease risk in Hispanic women from the Women's Health Initiative

Journal article

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Dietary inflammatory index and cardiovascular disease risk in Hispanic women from the Women's Health Initiative

Monica D Zuercher, Danielle J Harvey, Margarita Santiago-Torres, Lauren E Au, Nitin Shivappa, Aladdin H Shadyab, Matthew Allison, Linda Snetselaar, Buyun Liu, John A Robbins, …

Nutrition journal, Vol.22(1), 5

01/12/2023

DOI: 10.1186/s12937-023-00838-9

PMCID: PMC9835220

PMID: 36631866

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Abstract

To evaluate the association between the dietary inflammatory index (DII ) and incident cardiovascular disease (CVD) in Hispanic women from the Women's Health Initiative (WHI), and to determine if body mass index (BMI) interacted with the DII scores. Secondary analysis of baseline dietary data and long-term CVD outcomes among 3,469 postmenopausal women who self-identified as Hispanic enrolled in WHI. DII scores were calculated from self-administered food frequency questionnaires. The CVD outcomes included coronary heart disease (CHD) and stroke. Stratified Cox regression models were used to assess the relationship between DII scores and CVD in women with and without obesity. Models were adjusted for age, lifestyle risk factors, known risk factors, and neighborhood socioeconomic status. The incidence of CHD was 3.4 and 2.8% for stroke after a median follow-up of 12.9 years. None of the DIIs were associated with CVD risk in this sample of Hispanic women. BMI interacted with the DII (p < 0.20) and stratified models showed that the associations between the DII and CVD were only significant in women with overweight (p < 0.05). In this group, higher DII scores were associated with a higher risk of CHD (HR 1.27; 95% CI: 1.08, 1.51) and a higher risk of stroke (HR 1.32; 95% CI: 1.07, 1.64). Among postmenopausal Hispanic women with overweight, greater adherence to pro-inflammatory diets was associated with higher risk of CVD. Additional research is needed to understand how to promote long-term heart-healthy dietary habits to reduce inflammation and prevent CVD in at-risk Hispanic women.

Stroke

Cardiovascular Diseases - prevention & control

Coronary Disease - epidemiology

Diet

Female

Hispanic or Latino

Humans

Inflammation - complications

Inflammation - epidemiology

Overweight - complications

Risk Factors

Women's Health

Details

Title: Subtitle: Dietary inflammatory index and cardiovascular disease risk in Hispanic women from the Women's Health Initiative
Creators: Monica D Zuercher - University of California, Davis
Danielle J Harvey - University of California, Davis
Margarita Santiago-Torres - Fred Hutch Cancer Center
Lauren E Au - University of California, Davis
Nitin Shivappa - University of South Carolina
Aladdin H Shadyab - Human Longevity (United States)
Matthew Allison - University of California San Diego
Linda Snetselaar - University of Iowa
Buyun Liu - University of Iowa
John A Robbins - University of California, Davis
James R Hébert - University of South Carolina
Lorena Garcia - University of California, Davis
Resource Type: Journal article
Publication Details: Nutrition journal, Vol.22(1), 5
DOI: 10.1186/s12937-023-00838-9
PMID: 36631866
PMCID: PMC9835220
NLM abbreviation: Nutr J
ISSN: 1475-2891
eISSN: 1475-2891
Language: English
Date published: 01/12/2023
Academic Unit: Epidemiology; Fraternal Order of Eagles Diabetes Research Center; Internal Medicine
Record Identifier: 9984360035202771

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