Journal article
Differences in prostate cancer treatment receipt and timeliness of treatment between African American/Black and White Iowans
Cancer causes & control, Vol.36(12), pp.2001-2014
12/2025
DOI: 10.1007/s10552-025-02064-6
PMCID: PMC12630164
PMID: 41082031
Appears in UI Libraries Support Open Access
Abstract
Non-Hispanic Black (NHB) men face higher prostate cancer (PCa) mortality rates compared to other racial/ethnic groups. Factors contributing to these disparities, particularly concerning healthcare system factors, remain uncertain. We investigate differences in treatment receipt and timeliness between NHB, non-Hispanic White (NHW) and Hispanic Iowans, examining variations across treatment facilities.
Demographic, tumor, treatment, and hospital characteristics of PCa patients 40-99 years were obtained from the Iowa Cancer Registry (2010-2020). We used logistic regression to estimate the odds of receiving definitive treatment, time to treatment, and the type of treatment received.
Among 18,747 PCa patients, 18,197 (97.1%) were NHW, 550 (2.9%) NHB, and 155 Hispanic (0.83%). NHB men were younger. The odds of receiving definitive treatment among advanced stage patients were significantly lower for NHBs compared to NHWs (adjusted odds ratio-AOR- 0.39; 95% CI 0.26-0.59). More NHBs underwent PCa treatment at either NCI-designated or CoC-accredited facilities. NHBs receiving care at an NCI-designated center or at a non-accredited center were less likely to receive definitive treatment compared to NHWs. Furthermore, NHBs with advanced PCa had diminished odds of receiving definitive treatment regardless of the status of the treatment facility (NCI: AOR = 0.34; 95% CI 0.13 - 0.93; CoC only: AOR = 0.47; 95% CI 0.29 - 0.76; Neither: AOR 0.24; 95% CI 0.10-0.60).
NHB men with an advanced staging had lower odds of receiving definitive treatment across treatment settings. Further research and intervention are needed to reduce these disparities and improve PCa outcomes.
Details
- Title: Subtitle
- Differences in prostate cancer treatment receipt and timeliness of treatment between African American/Black and White Iowans
- Creators
- Gawain J Williams - University of IowaWhitney E Zahnd - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Cancer causes & control, Vol.36(12), pp.2001-2014
- DOI
- 10.1007/s10552-025-02064-6
- PMID
- 41082031
- PMCID
- PMC12630164
- NLM abbreviation
- Cancer Causes Control
- ISSN
- 1573-7225
- eISSN
- 1573-7225
- Publisher
- Springer Nature
- Grant note
- Iowa Cancer Registry/ State Health Registry of Iowa National Cancer Institute, National Institutes of Health, Department of Health and Human Services: HHSN261201800012I University of Iowa State of Iowa
The authors declare that no funds, grants, or other support were received during the preparation of this manuscript. The Iowa Cancer Registry/ State Health Registry of Iowa is funded in whole or in part with Federal funds from the National Cancer Institute, National Institutes of Health, Department of Health and Human Services, under Contract No. HHSN261201800012I and in part with funds from the University of Iowa and funds from the State of Iowa.
- Language
- English
- Electronic publication date
- 10/13/2025
- Date published
- 12/2025
- Academic Unit
- Health Management and Policy
- Record Identifier
- 9985015822802771
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