Journal article
Different effects of vasopressin and angiotensin II on baroreflexes
Federation proceedings, Vol.44(8), pp.2388-2392
05/1985
PMID: 3987916
Abstract
Our data indicate that vasopressin facilitates baroreflex inhibition of lumbar sympathetic nerve activity by two mechanisms: it sensitizes baroreceptors locally and shifts the stimulus-response curve so that a lower carotid sinus pressure results in a certain level of reflex sympathetic inhibition; it also produces a corresponding shift when given i.v. and excluded from baroreceptors implicating a second, central mechanism for facilitation of baroreflexes. In contrast, angiotensin II attenuates baroreflex inhibition of peripheral sympathetic function and this is accounted for totally by a central action. Why these differences occur present challenging new questions for future investigation.
Details
- Title: Subtitle
- Different effects of vasopressin and angiotensin II on baroreflexes
- Creators
- P G SchmidG B GuoF M Abboud
- Resource Type
- Journal article
- Publication Details
- Federation proceedings, Vol.44(8), pp.2388-2392
- Publisher
- United States
- PMID
- 3987916
- ISSN
- 0014-9446
- Grant note
- HL14388 / NHLBI NIH HHS HL20768 / NHLBI NIH HHS
- Language
- English
- Date published
- 05/1985
- Academic Unit
- Molecular Physiology and Biophysics; Cardiovascular Medicine; Fraternal Order of Eagles Diabetes Research Center; Internal Medicine
- Record Identifier
- 9984025326402771
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