Different release modes of α-tectorin contribute to the development of the tectorial membrane

Bernd Fritzsch; Ebenezer N Yamoah

doi:10.1016/j.devcel.2025.02.007

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Different release modes of α-tectorin contribute to the development of the tectorial membrane

Journal article

Peer reviewed

Different release modes of α-tectorin contribute to the development of the tectorial membrane

Bernd Fritzsch and Ebenezer N Yamoah

Developmental cell, Vol.60(5), pp.665-666

03/10/2025

DOI: 10.1016/j.devcel.2025.02.007

PMID: 40068602

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Abstract

The tectorial membrane extracellular matrix in the cochlea controls auditory transduction, but its earliest development remains unclear. In this issue of Developmental Cell, Niazi et al. have provided insight into tectorial membrane formation, demonstrating proteolytic shedding early in development and interaction with α-tectorin and collagen.

Animals

Cochlea - growth & development

Cochlea - metabolism

Collagen - metabolism

Extracellular Matrix - metabolism

Extracellular Matrix Proteins - metabolism

Humans

Tectorial Membrane - metabolism

Details

Title: Subtitle: Different release modes of α-tectorin contribute to the development of the tectorial membrane
Creators: Bernd Fritzsch - University of Nebraska Medical Center
Ebenezer N Yamoah - University of Arizona
Resource Type: Journal article
Publication Details: Developmental cell, Vol.60(5), pp.665-666
DOI: 10.1016/j.devcel.2025.02.007
PMID: 40068602
NLM abbreviation: Dev Cell
ISSN: 1534-5807
eISSN: 1878-1551
Publisher: CELL PRESS
Language: English
Date published: 03/10/2025
Academic Unit: Biology; Craniofacial Anomalies Research Center
Record Identifier: 9984799679902771

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