Journal article
Differentiation of ischemic from non-ischemic central retinal vein occlusion during the early acute phase
Graefe's archive for clinical and experimental ophthalmology, Vol.228(3), pp.201-217
1990
DOI: 10.1007/BF00920022
PMID: 2361592
Abstract
We investigated prospectively in 128 patients (140 eyes) the role of six routine clinical tests in the differentiation of ischemic central retinal vein occlusion (CRVO) from non-ischemic CRVO during its early acute phase. There were four functional tests [visual acuity, visual fields, relative afferent pupillary defect (RAPD), electroretinography (ERG)] and two morphologic tests (ophthalmoscopy and fluorescein fundus angiography). We found that none of the six tests had 100% sensitivity and specificity in such a differentiation during the early, acute phase, so that no one test can be considered a "gold standard"; however, combined information from all six is almost always reliable. Overall, the four functional tests proved far superior to the two morphologic tests in differentiating ischemic from non-ischemic CRVO:RAPD was most reliable in uniocular CRVO (with a normal fellow eye), followed closely by ERG in all cases; combined information from RAPD and ERG differentiated 97% of cases; perimetry was the next most reliable, followed by visual acuity. The two morphologic tests performed worst; fluorescein angiography provided either no information at all on retinal capillary nonperfusion (in at least one-third of the eyes during the early, acute phase) because of multiple limitations, or sometimes provided misleading information. Ophthalmoscopic appearance is the least reliable, most misleading parameter.
Details
- Title: Subtitle
- Differentiation of ischemic from non-ischemic central retinal vein occlusion during the early acute phase
- Creators
- Sohan Singh Hayreh - University of IowaMarie R Klugman - University of IowaMeena Beri - University of IowaAlan E Kimura - University of IowaPatricia Podhajsky - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Graefe's archive for clinical and experimental ophthalmology, Vol.228(3), pp.201-217
- DOI
- 10.1007/BF00920022
- PMID
- 2361592
- ISSN
- 0721-832X
- eISSN
- 1435-702X
- Language
- English
- Date published
- 1990
- Academic Unit
- Ophthalmology and Visual Sciences
- Record Identifier
- 9984182757702771
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