Journal article
Diffusion weighted magnetic resonance imaging of kidneys in children with vesicoureteral reflux
European journal of radiology, Vol.83(1), pp.e56-e60
01/01/2014
DOI: 10.1016/j.ejrad.2013.09.029
PMID: 24161782
Abstract
The apparent diffusion coefficient (ADC) which obtain from diffusion-weighted magnetic resonance imaging (DWI), is a quantitative parameter representing the renal function and parenchymal damage in some renal disorders. The primary aim of this study was to investigate whether renal tissue alterations associated with vesicoureteral reflux (VUR) can be displayed by DWI. The secondary aim was to assess how ADC values change with age in kidneys with and without VUR.
This prospective study included 46 patients (8 boys, 38 girls; mean age 7.3±4.2; range 1–15 years) with VUR and 54 control subjects (21 boys, 33 girls; mean age 7.7±5.2; range 1–17 years). All subjects underwent DWI of the kidneys using b value of 600s/mm2 in addition to MR urography. The ADC values of 71 kidneys with VUR were compared with those of 81 kidneys without VUR.
The mean ADC values were (1.93±0.36)×10−3mm2/s, (1.97±0.24)×10−3mm2/s, (1.83±0.37)×10−3mm2/s, (1.98±0.20)×10−3mm2/s and (2.08±0.42)×10−3mm2/s in normal kidneys, and in those with grade 1, grade 2, grade 3 and grade 4 VUR, respectively. There was no significant difference in ADC values between kidneys with and without VUR. There was a significant positive correlation between the age and ADC values both in kidneys with and without VUR (r=0.79, p<0.001 and r=0.82; p<0.001, respectively).
DWI does not reveal probable parenchymal alterations in reflux nephropathy. ADC values increase with age during childhood not only in normal kidneys but also in kidneys with VUR.
Details
- Title: Subtitle
- Diffusion weighted magnetic resonance imaging of kidneys in children with vesicoureteral reflux
- Creators
- Ali Koçyiğit - Pamukkale UniversityRecep Bayram - Pamukkale UniversitySelçuk Yüksel - Pamukkale Universityİsmail Yılmaz - Pamukkale UniversityNevzat Karabulut - Pamukkale University
- Resource Type
- Journal article
- Publication Details
- European journal of radiology, Vol.83(1), pp.e56-e60
- Publisher
- Elsevier Ireland Ltd
- DOI
- 10.1016/j.ejrad.2013.09.029
- PMID
- 24161782
- ISSN
- 0720-048X
- eISSN
- 1872-7727
- Language
- English
- Date published
- 01/01/2014
- Academic Unit
- Radiology
- Record Identifier
- 9984697634402771
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