Journal article
Direct Recordings of Pitch Responses from Human Auditory Cortex
Current biology, Vol.20(12), pp.1128-1132
06/22/2010
DOI: 10.1016/j.cub.2010.04.044
PMCID: PMC3221038
PMID: 20605456
Abstract
Pitch is a fundamental percept with a complex relationship to the associated sound structure [1]. Pitch perception requires brain representation of both the structure of the stimulus and the pitch that is perceived. We describe direct recordings of local field potentials from human auditory cortex made while subjects perceived the transition between noise and a noise with a regular repetitive structure in the time domain at the millisecond level called regular-interval noise (RIN) [2]. RIN is perceived to have a pitch when the rate is above the lower limit of pitch [3], at approximately 30 Hz. Sustained time-locked responses are observed to be related to the temporal regularity of the stimulus, commonly emphasized as a relevant stimulus feature in models of pitch perception (e.g., [1]). Sustained oscillatory responses are also demonstrated in the high gamma range (80–120 Hz). The regularity responses occur irrespective of whether the response is associated with pitch perception. In contrast, the oscillatory responses only occur for pitch. Both responses occur in primary auditory cortex and adjacent nonprimary areas. The research suggests that two types of pitch-related activity occur in humans in early auditory cortex: time-locked neural correlates of stimulus regularity and an oscillatory response related to the pitch percept.
► We report direct recordings of electrical activity from human auditory cortex ► We distinguish activity related to stimulus regularity and to perceived pitch ► Both are demonstrated in primary cortex and adjacent “core” areas
Details
- Title: Subtitle
- Direct Recordings of Pitch Responses from Human Auditory Cortex
- Creators
- Timothy D Griffiths - Institute of Neuroscience, Newcastle University Medical School, Framlington Place, Newcastle upon Tyne NE2 4HH, UKSukhbinder Kumar - Institute of Neuroscience, Newcastle University Medical School, Framlington Place, Newcastle upon Tyne NE2 4HH, UKWilliam Sedley - Institute of Neuroscience, Newcastle University Medical School, Framlington Place, Newcastle upon Tyne NE2 4HH, UKKirill V Nourski - Department of Neurosurgery, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242-1061, USAHiroto Kawasaki - Department of Neurosurgery, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242-1061, USAHiroyuki Oya - Department of Neurosurgery, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242-1061, USARoy D Patterson - Centre for the Neural Basis of Hearing, Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3EG, UKJohn F Brugge - Department of Neurosurgery, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242-1061, USAMatthew A Howard - Department of Neurosurgery, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242-1061, USA
- Resource Type
- Journal article
- Publication Details
- Current biology, Vol.20(12), pp.1128-1132
- DOI
- 10.1016/j.cub.2010.04.044
- PMID
- 20605456
- PMCID
- PMC3221038
- NLM abbreviation
- Curr Biol
- ISSN
- 0960-9822
- eISSN
- 1879-0445
- Publisher
- Elsevier Inc
- Language
- English
- Date published
- 06/22/2010
- Academic Unit
- Neurology; Psychological and Brain Sciences; Iowa Neuroscience Institute; Neurosurgery; Otolaryngology
- Record Identifier
- 9984014018002771
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