Discriminative ability of dual-energy X-ray absorptiometry site selection in identifying patients with osteoporotic fractures

Asma Arabi; Rafic Baddoura; Hassane Awada; Nabil Khoury; Souha Haddad; Ghazi Ayoub; Ghada El-Hajj Fuleihan

doi:10.1016/j.bone.2006.11.017

$Discriminative ability of dual-energy X-ray absorptiometry site selection in identifying patients with osteoporotic fractures$

Journal article

Peer reviewed

Discriminative ability of dual-energy X-ray absorptiometry site selection in identifying patients with osteoporotic fractures

Asma Arabi, Rafic Baddoura, Hassane Awada, Nabil Khoury, Souha Haddad, Ghazi Ayoub and Ghada El-Hajj Fuleihan

Bone (New York, N.Y.), Vol.40(4), pp.1060-1065

04/01/2007

DOI: 10.1016/j.bone.2006.11.017

PMID: 17223616

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Abstract

Dual-energy X-ray absorptiometry (DXA) is the gold standard method for measurement of bone mineral density (BMD). The aims of the current study are to compare the ability of BMD measurements to identify subjects with vertebral fractures (VF), when the lumbar spine (LS), hip or both sites are measured. 460 subjects aged 73 ± 5.2 years participated in the study. Thoraco-lumbar spine radiographs were obtained and analyzed for the presence of VF using the visual semi-quantitative assessment. BMD of the LS and the left femur were measured by DXA. Eighteen men (12%) and 56 women (20%) had at least one VF. 16% of scans at the LS were unreadable because of the presence of degenerative changes. In both genders, BMD of the hip showed better ability than LS BMD in detecting subjects with osteoporosis. BMD and T-score values at the hip, but not the LS, were lower in subjects with VF than those without ( p < 0.05). Femoral neck BMD showed the highest OR for each S.D. decrease in BMD for identifying subjects with VF, and the best predictability for prevalent VF using ROC. Fracture risk prediction did not increase by adding the spine to the hip measurement. In conclusion, hip BMD was the only and best skeletal site needed to detect subjects with osteoporosis and showed the strongest relationship with prevalent vertebral fractures in elderly subjects.

BMD

Hip

Relative risk

Spine

Vertebral fractures

Details

Title: Subtitle: Discriminative ability of dual-energy X-ray absorptiometry site selection in identifying patients with osteoporotic fractures
Creators: Asma Arabi - American University of Beirut Medical Center
Rafic Baddoura - Saint Joseph University
Hassane Awada - Saint Joseph University
Nabil Khoury - American University of Beirut Medical Center
Souha Haddad - Saint Joseph University
Ghazi Ayoub - Saint Joseph University
Ghada El-Hajj Fuleihan - American University of Beirut Medical Center
Resource Type: Journal article
Publication Details: Bone (New York, N.Y.), Vol.40(4), pp.1060-1065
Publisher: Elsevier Inc
DOI: 10.1016/j.bone.2006.11.017
PMID: 17223616
ISSN: 8756-3282
eISSN: 1873-2763
Language: English
Date published: 04/01/2007
Academic Unit: Radiology
Record Identifier: 9984697630502771

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