Journal article
Disseminated CD8-positive, CD30-positive cutaneous lymphoproliferative eruption with overlapping features of mycosis fungoides and primary cutaneous anaplastic large cell lymphoma following remote solitary lesional presentation
Journal of cutaneous pathology, Vol.44(8), pp.703-712
08/2017
DOI: 10.1111/cup.12961
PMID: 28497585
Abstract
CD8-positive, CD30-positive cutaneous lymphoproliferative disorders constitute a rare subset of T-cell lymphoproliferative conditions, including variants of primary cutaneous anaplastic large cell lymphoma (ALCL), mycosis fungoides, lymphomatoid papulosis type D, cutaneous gamma-delta T-cell lymphoma and cutaneous peripheral T-cell lymphoma. These entities share overlapping clinical, histopathologic and immunophenotypic features, presenting both a clinical and pathological diagnostic challenge. Presented here is a 73-year-old man with a disseminated, indolent CD30+, CD8+ cutaneous lymphoproliferative disorder with overlapping clinical and histopathological features of both mycosis fungoides and primary cutaneous ALCL, as well as features of lymphomatoid papulosis. To our knowledge, this is the first case of a generalized CD8+, CD30+ eruption with features of both mycosis fungoides and primary cutaneous ALCL arising following an episode of solitary primary cutaneous CD8-positive ALCL.
Details
- Title: Subtitle
- Disseminated CD8-positive, CD30-positive cutaneous lymphoproliferative eruption with overlapping features of mycosis fungoides and primary cutaneous anaplastic large cell lymphoma following remote solitary lesional presentation
- Creators
- Jonathan J Davick - Department of Pathology, University of Virginia, Charlottesville, VirginiaKrishna A J Mutgi - Department of Dermatology, University of Iowa Hospitals and Clinics, Iowa City, IowaKarolyn A Wanat - Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, IowaBrian K Link - Department of Medicine, Division of Hematology-Oncology, University of Iowa Hospitals and Clinics, Iowa City, IowaVincent Liu - Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, Iowa
- Resource Type
- Journal article
- Publication Details
- Journal of cutaneous pathology, Vol.44(8), pp.703-712
- Publisher
- United States
- DOI
- 10.1111/cup.12961
- PMID
- 28497585
- ISSN
- 0303-6987
- eISSN
- 1600-0560
- Grant note
- P30 CA086862 / NCI NIH HHS
- Language
- English
- Date published
- 08/2017
- Academic Unit
- Dermatology; Hematology, Oncology, and Blood & Marrow Transplantation; Pathology; Internal Medicine
- Record Identifier
- 9984025317802771
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