Distribution of neurofilament proteins in the lateral geniculate nucleus, primary visual cortex, and area MT of adult Cebus monkeys

Juliana Guimarães Martins Soares; Paulo Henrique Rosado De Castro; Mario Fiorani; Sheila Nascimento-Silva; Ricardo Gattass

doi:10.1002/cne.21718

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Distribution of neurofilament proteins in the lateral geniculate nucleus, primary visual cortex, and area MT of adult Cebus monkeys

Journal article

Peer reviewed

Distribution of neurofilament proteins in the lateral geniculate nucleus, primary visual cortex, and area MT of adult Cebus monkeys

Juliana Guimarães Martins Soares, Paulo Henrique Rosado De Castro, Mario Fiorani, Sheila Nascimento-Silva and Ricardo Gattass

Journal of comparative neurology (1911), Vol.508(4), pp.605-614

06/01/2008

DOI: 10.1002/cne.21718

PMID: 18383052

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Abstract

We investigated the distribution pattern of SMI-32-immunopositive cells in the lateral geniculate nucleus (LGN) and in the primary (V1) and middle temporal (MT) cortical visual areas of the adult New World monkey Cebus apella. In the LGN, the reaction for SMI-32 labeled cells in both the magnocellular (M) and parvocellular (P) layers. However, the cellular label was heavier in M layers, which also showed a more intense labeling in the neuropil. In V1, the reaction showed a lamination pattern, with the heaviest labeling occurring in layer 4B and upper layer 6 (layers that project to area MT). Area MT shows a dense band of labeled neuropil and large pyramidal neurons in layer 3, large darkly labeled but less densely packed neurons in layer 5, and a population of small, lightly labeled cells in layer 6. These results resemble those found in other New and Old World monkeys, which suggest that the preferential labeling of projection neurons associated with fast-conducting pathways to the extrastriate dorsal stream is a common characteristic of simian primates. In the superficial layers of V1 in Cebus monkeys, however, SMI-32-labeled neurons are found in both cytochrome oxidase blobs and interblob regions. In this aspect, our results in Cebus are similar to those found in the Old World monkey Macaca and different from those described for squirrel monkey, a smaller New World Monkey. In Cebus, as well as in Macaca, there is no correlation between SMI-32 distribution and the blob pattern.

Animals

Cebus - physiology

Female

Geniculate Bodies - chemistry

Geniculate Bodies - physiology

Male

Neurofilament Proteins - analysis

Neurofilament Proteins - metabolism

Neurofilament Proteins - physiology

Visual Cortex - chemistry

Visual Cortex - physiology

Visual Pathways - chemistry

Visual Pathways - physiology

Details

Title: Subtitle: Distribution of neurofilament proteins in the lateral geniculate nucleus, primary visual cortex, and area MT of adult Cebus monkeys
Creators: Juliana Guimarães Martins Soares - Universidade Federal do Rio de Janeiro
Paulo Henrique Rosado De Castro
Mario Fiorani - Universidade Federal do Rio de Janeiro
Sheila Nascimento-Silva - Universidade Federal do Rio de Janeiro
Ricardo Gattass - Universidade Federal do Rio de Janeiro
Resource Type: Journal article
Publication Details: Journal of comparative neurology (1911), Vol.508(4), pp.605-614
DOI: 10.1002/cne.21718
PMID: 18383052
NLM abbreviation: J Comp Neurol
ISSN: 0021-9967
eISSN: 1096-9861
Language: English
Date published: 06/01/2008
Academic Unit: Radiology
Record Identifier: 9985143552402771

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