Journal article
Diversity in polyp pathology and distribution of Familial Juvenile Polyposis Syndrome
Saudi medical journal, Vol.23(3), pp.328-331
2002
PMID: 11938427
Abstract
Objective: Juvenile polyposis syndrome is a rare autosomal dominant disorder with incomplete penetrance. The aim of this study was to review our experience with juvenile polyposis syndrome with emphasis on the diversity of polyp pathology and distribution and the recommended treatment.
Methods: Over the period January 1994 through February 2001, 10 family members were managed at Princess Basma Teaching Hospital, Irbid, Jordan. Two siblings with juvenile polyposis syndrome are discussed.
Results: The polyps were unusually concentrated in the rectum. In one patient the polyps were purely of the adenomatous type. The father suffered from non-polyposis colon cancer at the age of 35.
Conclusion: Proctocolectomy and ileal pouch-anal anastomosis is recommended as the treatment of choice. Screening of juvenile polyposis syndrome patients and their relatives is emphasized for early detection of malignancy.
Details
- Title: Subtitle
- Diversity in polyp pathology and distribution of Familial Juvenile Polyposis Syndrome
- Creators
- Tareq M AL-JABERI - Department of General Surgery, Jordan University of Science and Technology, Irbid, JordanHatem EL-SHANTI - Department of Pediatrics, Jordan University of Science and Technology, Irbid, Jordan
- Resource Type
- Journal article
- Publication Details
- Saudi medical journal, Vol.23(3), pp.328-331
- Publisher
- Saudi Medical Journal
- PMID
- 11938427
- ISSN
- 0379-5284
- Language
- English
- Date published
- 2002
- Academic Unit
- Stead Family Department of Pediatrics; Medical Genetics and Genomics
- Record Identifier
- 9984093606902771
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