Journal article
Do Loneliness and Per Capita Income Combine to Increase the Pace of Biological Aging for Black Adults across Late Middle Age?
International journal of environmental research and public health, Vol.19(20), p.13421
10/17/2022
DOI: 10.3390/ijerph192013421
PMCID: PMC9602511
PMID: 36294002
Abstract
In a sample of 685 late middle-aged Black adults (M age at 2019 = 57.17 years), we examined the effects of loneliness and per capita income on accelerated aging using a newly developed DNA-methylation based index: the DunedinPACE. First, using linear, mixed effects regression in a growth curve framework, we found that change in DunedinPACE was dependent on age, with a linear model best fitting the data (b = 0.004,
p
< 0.001), indicating that average pace of change increased among older participants. A quadratic effect was also tested, but was non-significant. Beyond the effect of age, both change in loneliness (b = 0.009,
p
< 0.05) and change in per capita income (b = −0.016,
p
< 0.001) were significantly associated with change in DunedinPACE across an 11-year period, accounting for significant between person variability observed in the unconditional model. Including non-self-report indices of smoking and alcohol use did not reduce the association of loneliness or per capita income with DunedinPACE. However, change in smoking was strongly associated with change in DunedinPACE such that those reducing their smoking aged less rapidly than those continuing to smoke. In addition, both loneliness and per capita income were associated with DunedinPACE after controlling for variation in cell-types.
Details
- Title: Subtitle
- Do Loneliness and Per Capita Income Combine to Increase the Pace of Biological Aging for Black Adults across Late Middle Age?
- Creators
- Steven R. H. Beach - University of GeorgiaEric T. Klopack - University of IowaSierra E. Carter - Center for Family Research, The University of Georgia, Athens, GA 30602, USA Department of Psychology, The University of Georgia, Athens, GA 30602, USA Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90007, USA Department of Psychology, Georgia State University, Atlanta, GA 30302, USA College of Medicine, University of Iowa, Iowa City, IA 52242, USA Department of Sociology, The University of Georgia, Athens, GA 30602, USA Department of Psychological Sciences, University of Connecticut, Storrs, CT 06269, USARobert A. Philibert - University of IowaRonald L. Simons - University of IowaFrederick X. Gibbons - University of IowaMei Ling Ong - Center for Family Research, The University of Georgia, Athens, GA 30602, USA Department of Psychology, The University of Georgia, Athens, GA 30602, USA Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90007, USA Department of Psychology, Georgia State University, Atlanta, GA 30302, USA College of Medicine, University of Iowa, Iowa City, IA 52242, USA Department of Sociology, The University of Georgia, Athens, GA 30602, USA Department of Psychological Sciences, University of Connecticut, Storrs, CT 06269, USAMeg Gerrard - University of IowaMan-Kit Lei - University of Iowa
- Resource Type
- Journal article
- Publication Details
- International journal of environmental research and public health, Vol.19(20), p.13421
- DOI
- 10.3390/ijerph192013421
- PMID
- 36294002
- PMCID
- PMC9602511
- NLM abbreviation
- Int J Environ Res Public Health
- ISSN
- 1661-7827
- eISSN
- 1660-4601
- Publisher
- MDPI
- Grant note
- R01 CA220254 / National Cancer Institute and the National Institute on Minority Health and Health Disparities RF1 AG077386; R01 AG055393 / National Institute on Aging P50 DA051361 / National Institute on Drug Abuse
- Language
- English
- Date published
- 10/17/2022
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Psychiatry; Iowa Neuroscience Institute
- Record Identifier
- 9984307658902771
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