Journal article
Does Clinically Important Change in Function After Knee Replacement Guarantee Good Absolute Function? The Multicenter Osteoarthritis Study
Journal of rheumatology, Vol.41(1), pp.60-64
2014
DOI: 10.3899/jrheum.130313
PMCID: PMC3914207
PMID: 24293582
Abstract
Objective. Poor functional outcomes post–knee replacement are common, but estimates of its prevalence vary, likely in part because of differences in methods used to assess function. The agreement between improvement in function and absolute good levels of function after knee replacement has not been evaluated. We evaluated the attainment of improvement in function and absolute good function after total knee replacement (TKR) and the agreement between these measures.
Methods. Using data from The Multicenter Osteoarthritis (MOST) Study, we determined the prevalence of achieving a minimal clinically important improvement (MCII, ≥ 14.2/68 point improvement) and Patient Acceptable Symptom State (PASS, ≤ 22/68 post-TKR score) on the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Physical Function subscale at least 6 months after knee replacement. We also assessed the frequency of co-occurrence of the 2 outcomes, and the prevalence according to pre-knee replacement functional status.
Results. We included 228 subjects who had a knee replacement during followup (mean age 65 yrs, mean body mass index 33.4, 73% female). Seventy-one percent attained the PASS for function after knee replacement, while only 44% attained the MCII. Of the subjects who met the MCII, 93% also attained the PASS; however, of subjects who did not meet the MCII, 54% still achieved a PASS. Baseline functional status was associated with attainment of each MCII and PASS.
Conclusion. There was only partial overlap between attainment of a good level of function and actually improving by an acceptable amount. Subjects were more likely to attain an acceptable level of function than to achieve a clinically important amount of improvement post–knee replacement.
Details
- Title: Subtitle
- Does Clinically Important Change in Function After Knee Replacement Guarantee Good Absolute Function? The Multicenter Osteoarthritis Study
- Creators
- Jessica L MAXWELL - Boston University, United StatesDavid T FELSON - Boston University, United StatesJingbo Niu - Boston University, United StatesBarton WISE - University of California Davis, United StatesMichael C NEVITT - University of California, San Francisco, United StatesJasvinder A SINGH - University of Alabama, Birmingham, United StatesLaura FREY-LAW - University of Iowa, United StatesTuhina NEOGI - Boston University, United States
- Resource Type
- Journal article
- Publication Details
- Journal of rheumatology, Vol.41(1), pp.60-64
- Publisher
- Journal of Rheumatology Publishing; Toronto, ON
- DOI
- 10.3899/jrheum.130313
- PMID
- 24293582
- PMCID
- PMC3914207
- ISSN
- 0315-162X
- eISSN
- 1499-2752
- Language
- English
- Date published
- 2014
- Academic Unit
- Nursing; Physical Therapy and Rehabilitation Science
- Record Identifier
- 9984047774702771
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