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Does Pre-Operative Left Ventricular Function Predict Mitral Valve Function After Anomalous Left Coronary Artery From The Pulmonary Artery Repair?
Journal article   Open access   Peer reviewed

Does Pre-Operative Left Ventricular Function Predict Mitral Valve Function After Anomalous Left Coronary Artery From The Pulmonary Artery Repair?

Raji Venkitachalam, Katherine Cashen, Christopher W. Mastropietro, Liyun Zhang, Yan Ke, Peter C. Frommelt, Ronald Woods, Venu Amula, Aditya Badheka, Jason Buckley, …
JTCVS open, 101873
05/2026
DOI: 10.1016/j.xjon.2026.101873
url
https://doi.org/10.1016/j.xjon.2026.101873View
Published (Version of record) Open Access

Abstract

To compare the progression of mitral valve (MV) function before and after ALCAPA repair in those with preserved versus impaired left ventricular (LV) function. This is a post-hoc analysis of patients who underwent ALCAPA repair at 22 CoRe-PCICS centers.16,17 Mitral regurgitation (MR) severity was compared based on LV function at diagnosis and through 3 years of follow-up. Among 228 patients, 76 had normal/mild LV dysfunction, and 152 had moderate/severe LV dysfunction (median EF 60 vs 23%, p<0.0001). Preoperatively, >/=moderate MR was more common with moderate/severe LV dysfunction (51% vs 26%, p<0.001). At 3-year follow-up, those with >/= moderate MR decreased significantly in this group (51% to 13%; OR=0.11, 95%CI 0.05-0.25; p<0.0001), with no significant change in the normal/mild LV dysfunction group (26% to 16%; OR = 0.28, 95% CI 0.06-1.39; p=0.12). In patients with ALCAPA and MV dysfunction with preserved LV function, MV recovery is less common, highlighting the consideration for concomitant MV repair. [Display omitted]
 ALCAPA surgery concomitant mitral valve repair intermediate outcomes mitral regurgitation

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