Dose reduction with adaptive bolus chasing computed tomography angiography

Zhijun Cai; Er-Wei Bai; Ge Wang; Melhem J Sharafuddin; Hicham T Abada

doi:10.3233/XST-2010-0236

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Dose reduction with adaptive bolus chasing computed tomography angiography

Journal article

Peer reviewed

Dose reduction with adaptive bolus chasing computed tomography angiography

Zhijun Cai, Er-Wei Bai, Ge Wang, Melhem J Sharafuddin and Hicham T Abada

Journal of X-ray science and technology, Vol.18(1), pp.15-25

2010

DOI: 10.3233/XST-2010-0236

PMCID: PMC2868330

PMID: 20421701

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http://doi.org/10.3233/XST-2010-0236View

Open Access

Abstract

Computed Tomography (CT) has become an effective diagnosis and evaluating tool in clinical; however, its radiation exposure has drawn great attention as more and more CT scans are performed every year. How to reduce the radiation dose and meanwhile keep the resultant CT images diagnosable becomes an important research topic. In this paper, we propose a dose reduction approach along with the adaptive bolus chasing CT Angiography (CTA) techniques, which are capable of tracking the contrast bolus peak over all the blood vessel segments during the CTA scan. By modulating the tube current (and collimator width) online, we can reduce the total radiation dose and maintain the contrast to noise ratio (CNR) of the blood vessel. Numerical experiments on reference DSA data sets show that by using the proposed dose reduction method, the effective radiation dose can be saved about 39%.

Algorithms

Radiographic Image Interpretation, Computer-Assisted - methods

Angiography, Digital Subtraction - methods

Computer Simulation

Humans

Tomography, X-Ray Computed - methods

Radiation Dosage

Dose-Response Relationship, Radiation

Vascular Diseases - diagnosis

Details

Title: Subtitle: Dose reduction with adaptive bolus chasing computed tomography angiography
Creators: Zhijun Cai - Department of Electrical and Computer Engineering, University of Iowa, Iowa City, IA 52242, USA
Er-Wei Bai
Ge Wang
Melhem J Sharafuddin
Hicham T Abada
Resource Type: Journal article
Publication Details: Journal of X-ray science and technology, Vol.18(1), pp.15-25
DOI: 10.3233/XST-2010-0236
PMID: 20421701
PMCID: PMC2868330
NLM abbreviation: J Xray Sci Technol
ISSN: 0895-3996
eISSN: 1095-9114
Publisher: Netherlands
Grant note: R21 EB004287 / NIBIB NIH HHS R33 EB004287-05 / NIBIB NIH HHS R33 EB004287 / NIBIB NIH HHS R21 EB004287-01 / NIBIB NIH HHS R33 EB004287-04 / NIBIB NIH HHS R33 EB004287-02 / NIBIB NIH HHS R33 EB004287-03 / NIBIB NIH HHS
Language: English
Date published: 2010
Academic Unit: Radiology; Electrical and Computer Engineering; Surgery
Record Identifier: 9984051563902771

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