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Dosimetric comparison of DEFGEL and PAGAT formulae paired with an MRI acquisition
Journal article   Open access

Dosimetric comparison of DEFGEL and PAGAT formulae paired with an MRI acquisition

Charles Matrosic, Alan McMillan, James Holmes, Bryan Bednarz and Wesley Culberson
Journal of physics. Conference series, Vol.847(1), p.12012
2017
DOI: 10.1088/1742-6596/847/1/012012
PMCID: PMC6709699
PMID: 31452665
url
https://doi.org/10.1088/1742-6596/847/1/012012View
Published (Version of record) Open Access

Abstract

Normoxic Polyacrylamide Gels, or nPAGs, are 3D gel dosimeters that measure dose through the process of radiation-induced polymerization. Two nPAG formulae are DEFGEL and PAGAT, which are very similar, but differ mainly due to different weight fractions of monomers. The dosimetric resolutions of the two formulae when paired with a Spin-Echo (SE) MRI sequence and a monoexponential fit were compared over a range of 0-15 Gy. It was found that in the dose range 0-6 Gy the PAGAT formula generally showed a much finer dose resolution, while the DEFGEL formula showed a finer resolution from 8-15 Gy.

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